METHYL PHOSPHORODICHLORIDITE

METHYL PHOSPHORODICHLORIDITE
  • CAS No.:3279-26-3
Other grades of this product :
METHYL PHOSPHORODICHLORIDITE Basic information
Product Name:METHYL PHOSPHORODICHLORIDITE
Synonyms:METHYL DICHLOROPHOSPHITE, TECHNICAL GRADE;O-Methyl Phosphorodichloridite;Methoxydichlorophosphine;Methoxyphosphonous Dichloride;O-Methyl Phosphorodichloridit;Methyl Dichlorophosphite [Phosphitylating Agent];Methyl dichlorophosphite,98%;Methyl dichlorophosphite, 98% 5ML
CAS:3279-26-3
MF:CH3Cl2OP
MW:132.91
EINECS:221-915-3
Product Categories:Pyridine;All Aliphatics;Biochemistry;Nucleosides, Nucleotides & Related Reagents;Phosphorylating and Phosphorothioating Agents;Phosphorylation;Protecting Agents, Phosphorylating Agents & Condensing Agents;Synthetic Organic Chemistry;Aliphatics;Phosphorylating and Phosphitylating Agents;Building Blocks;Chemical Synthesis;Organic Building Blocks;Phosphorus Compounds;Phosphorus Halides
Mol File:3279-26-3.mol
METHYL PHOSPHORODICHLORIDITE Chemical Properties
Melting point -91 °C (lit.)
Boiling point 93-95 °C (lit.)
density 1.376 g/mL at 20 °C (lit.)
refractive index n20/D 1.474(lit.)
Fp 104 °F
storage temp. −20°C
form liquid
color Colorless to Almost colorless
Water Solubility Reacts with water. Soluble in chloroform, dichloromethane and ethyl acetate.
Sensitive Moisture Sensitive
BRN 1697452
Stability:Flammable.
CAS DataBase Reference3279-26-3(CAS DataBase Reference)
Safety Information
Hazard Codes C
Risk Statements 10-14-34-37
Safety Statements 26-36/37/39-45
RIDADR UN 2920 8/PG 2
WGK Germany 3
10-13-23
HazardClass 8
PackingGroup II
HS Code 29209090
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
METHYL PHOSPHORODICHLORIDITE Usage And Synthesis
Chemical PropertiesColourless Liquid
UsesEmployed in the synthesis of phosphorodichloridothioates1 and oxazaphosphorinanes2 from sulfenyl chlorides and a chiral amino alcohol, respectively.
UsesMethyl dichlorophosphite has been employed in the preparation of:
  • phosphonamidate- and phosphonate-linked phosphonopeptides
  • 2-(2-iodophenyl)ethyl methyl phosphite derivative of an alcohol
  • deoxyoligonucleotides on a polymer support
  • cis- and trans-2-oxo-2-propionyl-1,3,2-oxazaphosphorinane
  • phosphorodichloridothioates
  • oxazaphosphorinanes
METHYL PHOSPHORODICHLORIDITE Preparation Products And Raw materials

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