Azetidine hydrochloride

CAS No.：36520-39-5

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Azetidine hydrochloride Basic information

Product Name:	Azetidine hydrochloride
Synonyms:	AZETIDINE HCL;AZETIDINE HYDROCHLORIDE;TRIMETHYLENEIMINE HYDROCHLORIDE;Azetidine (trimethyleneimine) hydrochloride;Azetidine hydrochloride ,99%;Azetidine hydrochloride ,98%;Trimethylene imine hydrochloride, 1,3-Propylenimine hydrochloride, Azacyclobutane hydrochloride;azetadine hydrochloride
CAS:	36520-39-5
MF:	C3H8ClN
MW:	93.55
EINECS:	627-415-5
Product Categories:	Building Blocks;Chemical Synthesis;Amino Acids & Derivatives;Heterocyclic Building Blocks;N-Containing;Others;Heterocycles series;Heterocyclic Compounds;Azetidines;Heterocycles;Intermediates
Mol File:	36520-39-5.mol

Azetidine hydrochloride Chemical Properties

Melting point	>300 °C(lit.)
Fp	152 °C
storage temp.	Inert atmosphere,2-8°C
form	powder to crystal
color	White to Almost white
Water Solubility	Soluble in water (103.8°C at 760 mmHg).
Sensitive	Hygroscopic
CAS DataBase Reference	36520-39-5(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26
RIDADR	UN1325
WGK Germany	3
HazardClass	IRRITANT, HYGROSCOPIC
HS Code	29339900

MSDS Information

Provider	Language
SigmaAldrich	English

Azetidine hydrochloride Usage And Synthesis

Chemical Properties	White powder
Uses	Basic building block for synthesizing azetidines.1,2
Uses	Azetidine hydrochloride is a four-membered ring nitrogen-containing heterocycle. Useful building block in the synthesis of polypeptides and other nitrogen containing compounds with potential biological properties.
Uses	Azetidine hydrochloride is a building block for azetidine synthesis and a pharmaceutical intermediate.

Azetidine hydrochloride Preparation Products And Raw materials

Raw materials

Hydrochloric acid-->Ethyl acetate-->Methanol-->Sulfuric acid-->PETROLEUM ETHER-->Potassium carbonate-->Sodium chloride-->Palladium-->Hydrogen-->1-Butanol-->Epichlorohydrin-->Methanesulfonyl chloride-->tert-Butyl methyl ether-->1-Bromo-3-chloropropane-->Benzhydrylamine

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