Other grades of this product :
| Fisetin Basic information |
| Fisetin Chemical Properties |
| Melting point | >330 °C(lit.) | | Boiling point | 348.61°C (rough estimate) | | density | 1.2981 (rough estimate) | | refractive index | 1.4413 (estimate) | | storage temp. | Sealed in dry,Store in freezer, under -20°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | Colour Index | 75620 | | pka | 6.83±0.40(Predicted) | | color | Pale Yellow to Very Dark Yellow | | Merck | 14,4088 | | BRN | 292829 | | Stability: | Hygroscopic | | EPA Substance Registry System | Fisetin (528-48-3) |
| Risk Statements | 36/37/38 | | Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | LK9250000 | | F | 10 | | TSCA | Yes | | HS Code | 29329990 |
| Fisetin Usage And Synthesis |
| Chemical Properties | OCHRE POWDER | | Uses | Fisetin is used in biological studies as spleen tyrosine kinase inhibitors for autoimmune inflammation disease. This compound has neuroprotective properties. | | General Description | This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG | | Anticancer Research | Fisetin is a plant polyphenol from the flavonoid group. It occurs in fruits and vegetablesincluding persimmons, strawberries, onions, cucumbers, and apples. It is anantioxidant, exerts anticarcinogenic effects in HCT-116 (human colon carcinoma)cells, and modulates protein kinase and lipid kinase pathways (Wang et al. 2012).Fisetin alter signaling pathway like MAPK, NF-κB, activators of transcription(JAK/STAT), Janus kinase/signal transducers, phosphoinositide-3-kinase-proteinkinase (PI3K/Akt), Wnt, and mammalian target of rapamycin (mTOR), therebyleading to cell cycle arrest in HL-60 cells (human acute promyelocytic leukemiacells) (Singh et al. 2016b). Thus, it exhibits inhibitory effects on adhesion, migration,invasion, and multidrug resistance (Suh et al. 2009). |
| Fisetin Preparation Products And Raw materials |
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