2-Carboxyethyl acrylate

2-Carboxyethyl acrylate
  • CAS No.:24615-84-7

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  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
2-Carboxyethyl acrylate Basic information
Product Name:2-Carboxyethyl acrylate
Synonyms:.beta.-Carboxyethylacrylate;2-CARBOXYETHYL ACRYLATE;2-Carboxyethyl acrylate oligomers, n=0-3;β-Carboxyethyl acrylate;2-carboxyethyl acrylate oligomers;3-acryloyloxypropionic acid;B-Carboxyethyl acrylate;RARECHEM AL BO 0311
CAS:24615-84-7
MF:C6H8O4
MW:144.13
EINECS:246-359-9
Product Categories:monomer;AcrylateCarbonyl Compounds;Acrylic Monomers;C6 to C7;Esters;Monomers;Acrylate
Mol File:24615-84-7.mol
2-Carboxyethyl acrylate Chemical Properties
Boiling point 103 °C/19 mmHg (lit.)
density 1.214 g/mL at 25 °C (lit.)
refractive index n20/D 1.457(lit.)
Fp >230 °F
storage temp. 2-8°C
solubility H2O: soluble
pka3.95±0.10(Predicted)
PH2.95 (10wt. % in H2O)
Merck 13,132
EPA Substance Registry SystemHydracrylic acid acrylate (24615-84-7)
Safety Information
Hazard Codes C,Xi
Risk Statements 34-36/37/38
Safety Statements 23-26-36/37/39-45-36
RIDADR UN 3265 8/PG 2
WGK Germany 3
RTECS UD3325250
HS Code 29161290
MSDS Information
ProviderLanguage
SigmaAldrich English
2-Carboxyethyl acrylate Usage And Synthesis
Chemical PropertiesColorless to light yellow viscid liquid
Uses2-Carboxyethyl Acrylate is used in the preparation of DNase enzyme derivatives that act as potent preventative material of bacterial adhesion and biofilm formation in biomaterials.
Application2-Carboxyethyl acrylate can be polymerized in solution or emulsion to produce acrylic, vinyl acrylic, or styrene acrylic polymers, which are distinguished by their low glass transition temperatures (<30°C) as homopolymers. Greater elasticity, as well as improved adhesion.
PreparationSynthesis of 1-ethoxyethyl acrylate (EEA) and protected 2-carboxyethyl acrylate (proCEA)EEA and proCEA were synthesized following a previously published procedure and distilled prior to use. For the synthesis of proCEA (Figure 1), phosphoric acid (109 mg, 1.11 mmol) was weighed into a dry round bottom flask in a glovebox and then taken outside the glovebox, taking care that the phosphoric acid stayed dry. 2-Carboxyethyl acrylate (80 g, 555 mmol) and ethyl vinyl ether (48 g, 666 mmol) were added and the reaction was stirred for two days at room temperature. Hydrotalcite (Mg6Al2(OH)16CO3·4H2O, ~1 g) was added, stirred for one hour and filtered off. Excess ethyl vinyl ether was removed under reduced pressure and the product was distilled under reduced pressure (80 °C, 1.3 mbar).Figure 1 Synthesis of proCEA
HazardA severe skin irritant.
2-Carboxyethyl acrylate Preparation Products And Raw materials

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