S-(+)-2-Amino-1-propanol

S-(+)-2-Amino-1-propanol
  • CAS No.:2749-11-3
Other grades of this product :
S-(+)-2-Amino-1-propanol Basic information
Product Name:S-(+)-2-Amino-1-propanol
Synonyms:H-L-ALA-OL;H-ALANINOL;H-ALA-OL;H-ALA-OL S-(+)-2 AMINO-PROPANOL;2-AMINOPROPANOL;L-(+)-ALANINOL;L-ALANINOL;L-ALANILOL
CAS:2749-11-3
MF:C3H9NO
MW:75.11
EINECS:220-388-7
Product Categories:Amino Alcohols;Alcohols and Derivatives;Alanine [Ala, A];Amino Alcohols (Chiral);Chiral Building Blocks;Synthetic Organic Chemistry;Pharmaceutical Intermediates;Pharmaceutical Raw Materials;Chiral Compound;Amino alcohols;API;buildingblock
Mol File:2749-11-3.mol
S-(+)-2-Amino-1-propanol Chemical Properties
Melting point -2°C
Boiling point 72-73 °C11 mm Hg(lit.)
alpha 21.8 º (c=2,ethanol)
density 0.965 g/mL at 25 °C(lit.)
refractive index n20/D 1.450
Fp 145 °F
storage temp. Keep in dark place,Inert atmosphere,2-8°C
Water Solubility Completely miscible in water
pka12.88±0.10(Predicted)
form Oily Liquid
color Clear colorless to yellow
Specific Gravity0.96
optical activity[α]20/D +18°, neat
Sensitive Hygroscopic
BRN 1718865
CAS DataBase Reference2749-11-3(CAS DataBase Reference)
NIST Chemistry Reference1-Propanol, 2-amino-, (S)-(2749-11-3)
Safety Information
Hazard Codes C,Xi
Risk Statements 34-36/37/38
Safety Statements 26-36/37/39-45-36
RIDADR UN 2735 8/PG 2
WGK Germany 3
10-23
HazardClass 8
PackingGroup III
HS Code 29221990
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
S-(+)-2-Amino-1-propanol Usage And Synthesis
Chemical PropertiesColorless liquid
UsesS-(+)-2-Amino-1-propanol is an aliphatic amino alcohol shown to induce an antiproliferative effect in B16 melanoma cells. S-(+)-2-Amino-1-propanol is used in the preparation of oxazolines which are of ten used as ligands in homogeneous catalysis.
Uses(S)-(+)-2-Amino-1-propanol may be used in the preparation of unsymmetrical tridentate Schiff base ligands via condensation with carbonyl compounds. It may also be used as a chiral auxillary for the preparation of tert-butyl 4-N-[(2-hydroxy-1-(S)-methyl)ethylamino]-2-methylene-4-(S)-phenyl-butyrate.
DefinitionChEBI: An amino alcohol that is L-alanine in which the carboxy group has been reduced to the corresponding alcohol.
Purification MethodsPurify it as for S-2-amino-3-methylbutan-1-ol below. [Beilstein 4 IV 1615.]
S-(+)-2-Amino-1-propanol Preparation Products And Raw materials
Raw materialsL-Alanine
Preparation Products1-AdaMantanethylaMine-->ERGONOVINE-->Oxazole, 2,2'-(1-methylethylidene)bis[4,5-dihydro-4-methyl-, (4S,4'S)--->N-BENZYL-L-ALANINOL

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