8-BROMOADENOSINE

CAS No.：2946-39-6

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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8-BROMOADENOSINE Basic information

Product Name:	8-BROMOADENOSINE
Synonyms:	8-BROMOADENINE-9-BETA-D-RIBOFURANOSIDE;8-BROMOADENOSINE;6-AMINO-8-BROMOPURINE RIBOSIDE;(2R,3R,4S,5R)-2-(6-AMINO-8-BROMO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL;8-BROMOADENOSINE, HPLC PURIFIED, 98% PURE WITH HPLC UV CHROMATOGRAM;8-BROMO-D-ADENOSINE;6-Amino-8-bromopurine riboside, 8-Bromoadenine-9-β-D-ribofuranoside;8-Bromoadenosine,98%
CAS:	2946-39-6
MF:	C10H12BrN5O4
MW:	346.14
EINECS:	220-959-0
Product Categories:	Pyridines, Pyrimidines, Purines and Pteredines;Nucleotides and Nucleosides;Bases & Related Reagents;Nucleotides
Mol File:	2946-39-6.mol

8-BROMOADENOSINE Chemical Properties

Melting point	210-212 °C (dec.)(lit.)
Boiling point	717.7±70.0 °C(Predicted)
density	1.8171 (rough estimate)
refractive index	1.6400 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility	DMSO (Slightly), Methanol (Slightly, Sonicated)
pka	12.89±0.70(Predicted)
form	powder
color	white
Water Solubility	Soluble in DMSO, and DMF. Insoluble in water.
Sensitive	Air Sensitive
BRN	627737
CAS DataBase Reference	2946-39-6(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-24/25-22
WGK Germany	3
F	10-23
HS Code	2934 99 90

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

8-BROMOADENOSINE Usage And Synthesis

Description	8-Bromoadenosine is a nucleotide that is structurally related to adenosine. It can be used as an inhibitor of guanine nucleotide-binding proteins and has shown biological properties in vitro. 8-Bromoadenosine has been shown to inhibit the mitochondrial membrane potential, cytosolic Ca2+, and the synthesis of RNA and protein. 8-Bromoadenosine also inhibits leukemia inhibitory factor (LIF) production by 3T3-L1 preadipocytes and induces apoptosis in T84 cells.
Chemical Properties	Off-White Solid
Uses	8-Bromoadenosine is an adenosine binding inhibitor. formation of 8-S-L-cysteinyladenosine from 8-Bromoadenosine and cysteine.

8-BROMOADENOSINE Preparation Products And Raw materials

Preparation Products

8-CHLOROADENOSINE

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