Other grades of this product :
| BENZAMIDINE Basic information |
| BENZAMIDINE Chemical Properties |
| Melting point | 65-70 °C | | Boiling point | 208.5±23.0 °C(Predicted) | | density | 1.09±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | Chloroform (Slightly), Methanol (Slightly) | | pka | 11.90±0.40(Predicted) | | form | powder or crystals | | color | White to Off-White | | BRN | 606020 |
| Hazard Codes | Xn | | Risk Statements | 22-36 | | Safety Statements | 26 | | WGK Germany | 3 | | F | 9-23 | | HS Code | 29299000 |
| BENZAMIDINE Usage And Synthesis |
| Uses | Benzamidine was used in the preparation of heparan sulfate-rich proteoglycan from mouse mammary epithelial cells. It has been used to prevent enzymatic degradation during the purification procedure of bovine factor XII (Hageman factor). | | Synthesis Reference(s) | The Journal of Organic Chemistry, 27, p. 1255, 1962 DOI: 10.1021/jo01051a033Tetrahedron Letters, 31, p. 1969, 1990 DOI: 10.1016/S0040-4039(00)88891-7 | | Biochem/physiol Actions | Benzamidine is an inhibitor of plasmin and has been used in the radioimmunoassay of glucagon in human plasma. It prevents the destruction of Thyrotropin-releasing hormone (TRH) added to whole blood in vitro before radioimmunoassay of TRH. | | Purification Methods | It is liberated from its hydrochloride chloride (below) by treatment with 5M NaOH, extracted into diethyl ether, dried (Na2SO4) and sublimed in vacuo.[Beilstein 9 H 280, 9 I 123, 9 II 199, 9 1264, 9 IV 898.] |
| BENZAMIDINE Preparation Products And Raw materials |
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