6-Bromo-2-naphthol

CAS No.：15231-91-1

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
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6-Bromo-2-naphthol Basic information

Product Name:	6-Bromo-2-naphthol
Synonyms:	2-Naphthol, 6-bromo-;6-bromo-2-naphthaleno;6-bromo-2-naphtho;6-Bromo-beta-naphthol;Bromo-6 naphtol-2;bromo-6naphtol-2;6-BROMO-2-NAPHTHOL;6-BROMO-2-NAPHTHALENOL
CAS:	15231-91-1
MF:	C10H7BrO
MW:	223.07
EINECS:	239-279-0
Product Categories:	Building Blocks;C9 to C20+;Fused Ring Systems;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Aromatic Phenols;Heterocycles series;Halides;Phenoles and thiophenoles;Organic Building Blocks;Oxygen Compounds;Phenols;bc0001
Mol File:	15231-91-1.mol

6-Bromo-2-naphthol Chemical Properties

Melting point	122-124 °C (lit.)
Boiling point	130°C (rough estimate)
density	1.4412 (rough estimate)
refractive index	1.5700 (estimate)
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform, Methanol
form	Powder
pka	9.26±0.40(Predicted)
color	Off-white to beige
BRN	1100270
CAS DataBase Reference	15231-91-1(CAS DataBase Reference)
NIST Chemistry Reference	2-Naphthalenol, 6-bromo-(15231-91-1)
EPA Substance Registry System	6-Bromo-2-naphthol (15231-91-1)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-37/39
WGK Germany	3
RTECS	QL3365000
Hazard Note	Irritant
HS Code	29037990

MSDS Information

Provider	Language
6-Bromo-2-naphthol	English
ACROS	English
SigmaAldrich	English
ALFA	English

6-Bromo-2-naphthol Usage And Synthesis

Chemical Properties	off-white to beige powder
Uses	6-Bromo-2-naphthol is a flavonoid molecule that shows steroid hormone activity and may be useful on anticancer therapy.
Definition	ChEBI: A member of the class of naphthols that is 2-naphthol carrying an additional bromo substituent at position 6.
Purification Methods	Crystallise the naphthol from EtOH or *C6H6/pet ether (m 128o). The benzoyl derivative has m 122o, (from EtOH). [Ruggli & Michels Helv Chim Acta 14 779 1931, Beilstein 6 H 651, 6 II 605, 6 III 2996.]

6-Bromo-2-naphthol Preparation Products And Raw materials

Preparation Products

6-HYDROXY-2-NAPHTHALENEBORONIC ACID-->6-METHOXY-2-NAPHTHALENEBORONIC ACID-->6-FLUORO-2-NAPHTHOIC ACID-->2-Bromo-6-fluoronaphthalene-->NAFAMOSTAT MESYLATE-->6-BROMO-2-NAPHTHYL-BETA-D-GALACTOPYRANOSIDE-->6-BROMONAPHTHALEN-2-AMINE-->6-Propyl-2-naphthol-->2-Acetyl-6-bromonaphthalene-->PRODAN-->6-Hydroxy-2-naphthaldehyde-->(R)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol

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