2-Tetrahydrofurfurylamine

2-Tetrahydrofurfurylamine
  • CAS No.:4795-29-3
Other grades of this product :
2-Tetrahydrofurfurylamine Basic information
Product Name:2-Tetrahydrofurfurylamine
Synonyms:2-TETRAHYDROFURFURYLAMINE;2-AMINOMETHYL-TETRAHYDROFURAN;AKOS BBS-00003587;(n)-tetrahydrofurfurylamine;2-Tetrahydrofurylmethylamine;2-TETRAHYDROFURFURYLAMINE 98+%;(Tetrahydrofuran-2-ylmethyl)amine;2,3,4,5-Tetrahydrofuran-2-methanamine
CAS:4795-29-3
MF:C5H11NO
MW:101.15
EINECS:225-351-9
Product Categories:Furan&Benzofuran;Amines
Mol File:4795-29-3.mol
2-Tetrahydrofurfurylamine Chemical Properties
Melting point 136 °C
Boiling point 153-154 °C744 mm Hg(lit.)
density 0.98 g/mL at 25 °C(lit.)
refractive index n20/D 1.454(lit.)
Fp 114 °F
storage temp. Flammables area
solubility Chloroform, Methanol
pka9.47±0.29(Predicted)
form Liquid
color Clear colorless to light yellow
explosive limit1.6-14.1%(V)
Water Solubility miscible
Sensitive Air Sensitive & Hygroscopic
BRN 102729
CAS DataBase Reference4795-29-3(CAS DataBase Reference)
NIST Chemistry Reference2-Furanmethanamine, tetrahydro-(4795-29-3)
EPA Substance Registry SystemTetrahydrofurfurylamine (4795-29-3)
Safety Information
Hazard Codes Xi
Risk Statements 10-36/37/38
Safety Statements 26-36-37/39-16
RIDADR UN 2943 3/PG 3
WGK Germany 3
RTECS LV0175000
TSCA Yes
HazardClass 3
PackingGroup III
HS Code 29321900
MSDS Information
ProviderLanguage
2-Tetrahydrofurfurylamine English
ACROS English
SigmaAldrich English
ALFA English
2-Tetrahydrofurfurylamine Usage And Synthesis
Chemical PropertiesColorless to light-yellow liquid. Distilling range 150– 156C, d 0.977 (20C/20C). Combustible.
UsesChemical intermediate, fine-grain photographic development, vulcanization accelerator.
UsesTetrahydro-2-furanmethanamine is used in the synthesis of novel topoisomerase I targeting anti-cancer agents with mild to potent cytotoxic activity. Also used in the discovery and synthesis of orally bioavailable stearoyl-CoA desaturase 1 inhibitors
General DescriptionA colorless to light yellow liquid. Insoluble in water and less dense than water. Flash point between 100 - 141°F. Used to make other chemicals and as a photographic chemical.
Air & Water ReactionsFlammable. Insoluble in water.
Reactivity Profile2-Tetrahydrofurfurylamine is an amine and alcohol. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Health HazardMay cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Fire HazardHIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Safety ProfilePoison by intraperitoneal route. Flammable liquid when exposed to heat or flame. When heated to decomposition it emits toxic fumes of NOx. See also MINES.
2-Tetrahydrofurfurylamine Preparation Products And Raw materials

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