1-Naphthoyl chloride

CAS No.：879-18-5

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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1-Naphthoyl chloride Basic information

Product Name:	1-Naphthoyl chloride
Synonyms:	ALPHA-NAPHTHOYL CHLORIDE;TIMTEC-BB SBB006741;1-(Chlorocarbonyl)naphthalene;1-Naphthoic acid chloride;1-NAPHTHOYL CHLORIDE 98%;1-NAPHTHOYL CHLORIDE(ALPHA-) 99+%;1-NAPHTOHYL CHLORIDE;1-Naphthalenecarboxylic acid chloride
CAS:	879-18-5
MF:	C11H7ClO
MW:	190.63
EINECS:	212-903-9
Product Categories:	Naphthalene series;Miscellaneous;Acid Halides;Carbonyl Compounds;Organic Building Blocks
Mol File:	879-18-5.mol

1-Naphthoyl chloride Chemical Properties

Melting point	16-19 °C (lit.)
Boiling point	190 °C/35 mmHg (lit.)
density	1.265 g/mL at 25 °C (lit.)
refractive index	n20/D 1.652(lit.)
Fp	>230 °F
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
form	Powder, Flakes or Crystals
Specific Gravity	1.265
color	White to almost white
Water Solubility	Reacts with water.
Sensitive	Moisture Sensitive
BRN	775785
Stability:	Stable. Incompatible with water, moisture, strong oxidizing agents, bases.
CAS DataBase Reference	879-18-5(CAS DataBase Reference)
NIST Chemistry Reference	1-Naphthalenecarbonyl chloride(879-18-5)
EPA Substance Registry System	1-Naphthalenecarbonyl chloride (879-18-5)

Safety Information

Hazard Codes	C
Risk Statements	34-37-14
Safety Statements	26-36/37/39-45-28A-60-30-20-8
RIDADR	UN 3261 8/PG 2
WGK Germany	3
F	21
Hazard Note	Corrosive
TSCA	Yes
HazardClass	8
PackingGroup	II
HS Code	29163990

MSDS Information

Provider	Language
1-Naphthoyl chloride	English
SigmaAldrich	English
ACROS	English
ALFA	English

1-Naphthoyl chloride Usage And Synthesis

Chemical Properties	Low melting solid/Liquid
Uses	1-Naphthoyl chloride has been used as derivatization reagent in analysis of short-chained dodecyl alcohol ethoxylates and dodecyl alcohol by solid-phase extraction combined with dispersive liquid-liquid micro extraction method, as fluorescent labeling reagent in determination of T-2 and HT-2 toxins by HPLC with fluorescence detection, in Arndt-Eistert synthesis in the presence of trimethylsilyldiazomethane and in preparation of 2-ethyl-1-pentyl-3-(1-naphthoyl)indole.
Uses	1-Naphthoyl chloride has been used: as derivatization reagent in analysis of short-chained dodecyl alcohol ethoxylates and dodecyl alcohol by solid-phase extraction combined with dispersive liquid-liquid microextraction method as fluorescent labeling reagent in determination of T-2 and HT-2 toxins by HPLC with fluorescence detection in Arndt-Eistert synthesis in the presence of trimethylsilyldiazomethane in preparation of 2-ethyl-1-pentyl-3-(1-naphthoyl)indole

1-Naphthoyl chloride Preparation Products And Raw materials

Raw materials	Dichloromethane-->Thionyl chloride-->1-Naphthoic acid
Preparation Products	1-NAPHTHHYDRAZIDE-->4-Iodobenzoyl chloride

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