5-Bromo-2-methoxyphenol

5-Bromo-2-methoxyphenol
  • CAS No.:37942-01-1
Other grades of this product :
5-Bromo-2-methoxyphenol Basic information
Product Name:5-Bromo-2-methoxyphenol
Synonyms:5-BROMO-2-METHOXYPHENOL;3-HYDROXY-4-METHOXYBROMOBENZENE;5-Brom-2-methoxy-phenol;5-Bromo-2-methoxyphenol ,99%;5-Bromoguaiacol (OH=1);4-Bromo-2-hydroxyanisole;Phenol, 5-broMo-2-Methoxy-;4-Bromo-2-hydroxyanisole, 5-Bromoguaiacol
CAS:37942-01-1
MF:C7H7BrO2
MW:203.03
EINECS:609-492-7
Product Categories:blocks;Bromides
Mol File:37942-01-1.mol
5-Bromo-2-methoxyphenol Chemical Properties
Melting point 64-70
Boiling point 150 °C / 20mmHg
density 1.585±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
pka9.01±0.10(Predicted)
form powder to crystal
color White to Almost white
InChIKeyOLSJHVZRUFFIPL-UHFFFAOYSA-N
CAS DataBase Reference37942-01-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 20/21/22-36/37/38
Safety Statements 26-36/37/39
Hazard Note Irritant/Store Cold
HazardClass IRRITANT
HS Code 29095000
MSDS Information
5-Bromo-2-methoxyphenol Usage And Synthesis
Chemical PropertiesWhite to off-white crystal
UsesThe 5-Bromo-2-methoxyphenol is the important intermediate of producing depressor aliskiren.
SynthesisThe 5-bromo-2-methoxyphenol is synthesized by virtue of three steps of reactions as follows: by taking o-methoxyphenol as the raw materials, performing acetylation protection on the phenolic hydroxyl by use of acetic anhydride, and then performing bromination by use of bromine under the catalysis of iron powder, and finally performing deacetylation.

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