2,5-Dichlorophenol

2,5-Dichlorophenol
  • CAS No.:583-78-8

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
2,5-Dichlorophenol Basic information
Product Name:2,5-Dichlorophenol
Synonyms:2,5-dichloro-pheno;6-HYDROXY-1,4-DICHLOROBENZENE;2,5-DICHLORO-1-HYDROXY-BENZENE;2,5-DICHLOROPHENOL;2,5-DCP;DICHLOROPHENOL-2,5;Dichlorophenol,98%;2,5-DICHLOROPHENOL PESTANAL
CAS:583-78-8
MF:C6H4Cl2O
MW:163
EINECS:209-520-4
Product Categories:Aromatic Phenols;Organics;Phenol&Thiophenol&Mercaptan;Phenoles and thiophenoles;Chlorine Compounds;Phenols;Alpha sort;D;DAlphabetic;DIA - DIC;Pesticides&Metabolites;Organic Building Blocks;Oxygen Compounds;Volatiles/ Semivolatiles
Mol File:583-78-8.mol
2,5-Dichlorophenol Chemical Properties
Melting point 54-57 °C (lit.)
Boiling point 211 °C (lit.)
density 1.3446 (rough estimate)
refractive index 1.4430 (estimate)
Fp 100 °C
storage temp. 0-6°C
solubility 2000mg/l (experimental)
form Crystals
pka7.53±0.10(Predicted)
color White to light brown
Water Solubility 3 g/L (20 ºC)
BRN 1907692
LogP3.06 at 20℃
CAS DataBase Reference583-78-8(CAS DataBase Reference)
NIST Chemistry ReferencePhenol, 2,5-dichloro-(583-78-8)
EPA Substance Registry System2,5-Dichlorophenol (583-78-8)
Safety Information
Hazard Codes C,N,Xn
Risk Statements 22-34-51/53-36/38
Safety Statements 26-36/37/39-45-61-37/39
RIDADR UN 2020 6.1/PG 3
WGK Germany 2
RTECS SK8600000
TSCA Yes
HazardClass 6.1
PackingGroup III
HS Code 29081000
Hazardous Substances Data583-78-8(Hazardous Substances Data)
ToxicityLD50 orally in Rabbit: 580 mg/kg
MSDS Information
ProviderLanguage
2,5-Dichlorophenol English
SigmaAldrich English
ACROS English
ALFA English
2,5-Dichlorophenol Usage And Synthesis
Chemical Propertieswhite to light brown crystals
Uses2,5-Dichlorophenol is an intermediates in the manufacture of more complex chemical compounds such as fungicides.
Uses2,5-Dichlorophenol may be used as an analytical reference standard for the determination of the analyte in water, and wood, paper, cardboard, fruits, and fruit juices using simultaneous dispersive liquid-liquid microextraction and derivatization followed by gas chromatography-electron-capture detection (GC-ECD) and gas chromatography-mass spectrometry (GC-MS), respectively.
DefinitionChEBI: A dichlorophenol with the chloro substituents at positions 2 and 5.
Synthesis Reference(s)Journal of the American Chemical Society, 74, p. 3890, 1952 DOI: 10.1021/ja01135a052
General DescriptionPrisms (from benzene, petroleum ether) or white crystals. Odor threshold 30 μg/L at 68-72°F; 33 μg/L at 86°F. Taste threshold 0.5 μg/L.
Air & Water ReactionsInsoluble in water.
Reactivity Profile2,5-Dichlorophenol is incompatible with acid chlorides, acid anhydrides and oxidizing agents.
Fire HazardFlash point data for 2,5-Dichlorophenol are not available. 2,5-Dichlorophenol is probably combustible.
Purification MethodsCrystallise it from ligroin and sublime it in a vacuum or distil it. [Beilstein 6 IV 942.]

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