DIPROPYLENETRIAMINE

DIPROPYLENETRIAMINE
  • CAS No.:56-18-8
Other grades of this product :
DIPROPYLENETRIAMINE Basic information
Product Name:DIPROPYLENETRIAMINE
Synonyms:Bis(3-aminopropyl)amine,3,3′-Diaminodipropylamine, 3,3′-Iminodipropylamine, N-(3-Aminopropyl)-1,3-propanediamine, Dipropylenetriamine, Norspermidine;IMINODIPROPYLAMINE;IMINO BIS PROPYLAMINE;IBPA;DIPROPYLENETRIAMINE;dipropylamine,3,3’-diamino;Dipropylentriamin;Imino-bis(3-propylamine)
CAS:56-18-8
MF:C6H17N3
MW:131.22
EINECS:200-261-2
Product Categories:B;Bioactive Small Molecules;Building Blocks;Cell Biology;Chemical Synthesis;Nitrogen Compounds;Amines;Intermediates & Fine Chemicals;Pharmaceuticals;Organic Building Blocks;Polyamines
Mol File:56-18-8.mol
DIPROPYLENETRIAMINE Chemical Properties
Melting point −14 °C(lit.)
Boiling point 151 °C50 mm Hg(lit.)
density 0.938 g/mL at 25 °C(lit.)
refractive index n20/D 1.481(lit.)
Fp 245 °F
storage temp. 2-8°C
Water Solubility Completely miscible in water
form clear liquid
pkapK1:8.02(+2);pK2:9.70(+1);pK3:10.70(0) (30°C)
color Colorless to Almost colorless
BRN 1071254
Stability:Air and light sensitive. Combustible. Incompatible with oxidizing agents.
CAS DataBase Reference56-18-8(CAS DataBase Reference)
EPA Substance Registry SystemNorspermidine (56-18-8)
Safety Information
Hazard Codes T+,C
Risk Statements 22-24-26-35-43-68-48/20/21
Safety Statements 26-28-36/37/39-45
RIDADR UN 2269 8/PG 3
WGK Germany 2
RTECS JL9450000
HazardClass 8
PackingGroup III
HS Code 29252900
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
DIPROPYLENETRIAMINE Usage And Synthesis
Chemical Propertiescolourless to yellow liquid
UsesA structural homologue of the natural polyamine spermidine with antitumor activity that may make it useful as a antineoplastic agent.
UsesBis(3-aminopropyl)amine (BAPA) can be used:
  • To synthesize chitosan based hydrogels having potential biomedical applications.
  • For the functionalization of nanoparticles to yield terminal ?NH2 groups for further modifications.
  • As an internal dispersing agent for the synthesis of water-dispersible polyurethanes.
  • As a ligand in the preparation of [Cu(bapa)]2[Mo(CN)8]·7H2O photomagnetic coordination polymer.
Synthesis Reference(s)The Journal of Organic Chemistry, 58, p. 3736, 1993 DOI: 10.1021/jo00066a028Journal of the American Chemical Society, 105, p. 5002, 1983 DOI: 10.1021/ja00353a025
General DescriptionA colorless liquid. Less dense than water. Flash point of 170°F. Very irritating to skin and eyes, and may be toxic by ingestion. Used to make soaps, dyes, and pharmaceuticals.
Air & Water ReactionsWater soluble.
Reactivity ProfileDIPROPYLENETRIAMINE neutralize acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. DIPROPYLENETRIAMINE can react with oxidizing materials .
HazardToxic by ingestion and inhalation; irritant.
Health HazardTOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire HazardCombustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.
Safety ProfilePoison by skin contact. Moderately toxic by ingestion. A skin and severe eye irritant. When heated to decomposition it emits toxic fumes of NO,. An explosive
Purification MethodsDry the amine with Na and distil it under vacuum. [Beilstein 4 IV 1278.]

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