Diethyl (tosyloxy)methylphosphonate

Diethyl (tosyloxy)methylphosphonate
  • CAS No.:31618-90-3
Other grades of this product :
Diethyl (tosyloxy)methylphosphonate Basic information
Product Name:Diethyl (tosyloxy)methylphosphonate
Synonyms:DIETHYL 4-TOLUENESULFONYLOXYMETHYLPHOSPHONATE;diethyl [[[(4-tolyl)sulfonyl]oxy]methyl]phosphonate;(DIETHOXYPHOSPHORYL)METHYL 4-METHYLBENZENESULFONATE;[[[(4-Tolyl)sulfonyl]oxy]methyl]phosphonic acid diethyl ester;tosyloxymethyl diethyl phosphonate;TOLUENE-4-SULFONIC ACID DIETHOXY-PHOSPHORYLMETHYL ESTER;DESMP;DETHYL (TOSYLOXY) METHYLPHOSPHONATE
CAS:31618-90-3
MF:C12H19O6PS
MW:322.31
EINECS:608-653-9
Product Categories:Intermediates.;Phospholipids - 13C & 2H;Phosphorylating and Phosphitylating Agents
Mol File:31618-90-3.mol
Diethyl (tosyloxy)methylphosphonate Chemical Properties
Boiling point 137°C/0.02mmHg(lit.)
density 1.255
refractive index 1.4980 to 1.5020
storage temp. Inert atmosphere,2-8°C
solubility Chloroform (Sparingly), Dichloromethane, Ethyl Acetate, Methanol (Sparingly)
form Oil
color Clear Colourless to Pale Yellow
CAS DataBase Reference31618-90-3(CAS DataBase Reference)
Safety Information
Risk Statements 36/37/38
Safety Statements 36/37/39
HS Code 29309090
MSDS Information
Diethyl (tosyloxy)methylphosphonate Usage And Synthesis
Chemical PropertiesPale Yellow Oil
UsesDiethyl (tosyloxy)methylphosphonate is an antiviral agent and a Tenofovir intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor used as an anti-HIV agent.
UsesDiethyl p-Toluenesulfonyloxymethylphosphonate is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor used as an anti-HIV agent.
Diethyl (tosyloxy)methylphosphonate Preparation Products And Raw materials
Preparation ProductsDIETHYL IODOMETHYLPHOSPHONATE-->[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic acid diethyl ester

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