Other grades of this product :
| 1,3-Dimethylbarbituric acid Basic information |
| Product Name: | 1,3-Dimethylbarbituric acid | | Synonyms: | AKOS B029702;1,3-DIMETHYLPYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE;1,3-DIMETHYLBARBITURIC ACID;1,3-DIMETHYL-2,4,6(1H,3H,5H)-PYRIMIDINETRIONE;2,4,6(1H,3H,5H)-Pyrimidinetrione, 1,3-dimethyl-;6(1h,3h,5h)-pyrimidinetrione,1,3-dimethyl-4;1,3-DiMethylbarbituric acid, 98% 100GR;1,3-DiMethylbarbituric acid, 98% 25GR | | CAS: | 769-42-6 | | MF: | C6H8N2O3 | | MW: | 156.14 | | EINECS: | 212-211-7 | | Product Categories: | | Mol File: | 769-42-6.mol |
| 1,3-Dimethylbarbituric acid Chemical Properties |
| Hazard Codes | Xn | | Risk Statements | 22-41 | | Safety Statements | 26-36/39 | | WGK Germany | 3 | | TSCA | Yes | | HS Code | 29339900 |
| 1,3-Dimethylbarbituric acid Usage And Synthesis |
| Chemical Properties | Yellow or brownish powder | | Uses | 1,3-Dimethylbarbituric acid is used as a catalyst in the Knoevenagel condensation of a series of aromatic aldehydes. It is also used in the synthesis of 5-aryl-6-(alkyl- or aryl-amino)-1,3-dimethylfuro [2,3-d]pyrimidine derivatives and enantioselective synthesis of isochromene pyrimidinedione derivatives. | | Uses | 1,3-Dimethyl Barbituric Acid (Urapidil Impurity 4) is a derivative of Barbituric acid. All of the barbituric acid derivatives which have been reported to have pronounced hypnotic activity are disubstituted in the 5-position. | | General Description | 1,3-Dimethylbarbituric acid (1,3-Dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione) is an active methylene compound. It undergoes hollow Pd6 water-soluble cage, [{(tmen)Pd}6(timb)4](NO3)12 (tmen= N,N,N′,N′-tetramethylethylenediamine, timb=1,3,5-tris(1-imidazolyl)benzene)-catalyzed Knoevenagel condensation reaction with pyrene-1-carboxaldehyde. It undergoes self-sorted Pd7 molecular boat having an internal nanocavity (catalyst)-assisted Knoevenagel condensation reaction with various aromatic aldehydes. It has been synthesized by reacting 1,3-dimethylurea, malonic acid and acetic anhydride in acetic acid. It is widely used for the synthesis of various synthetic intermediates and heterocyclic compounds. | | Purification Methods | Crystallise the acid from water and sublime it in a vacuum. Also purify it by dissolving 10g in 100mL of boiling CCl4/CHCl3 (8:2) (1g charcoal), filtering and cooling to 25o. Dry it in vacuo [Kohn et al. Anal Chem 58 3184 1986]. [Beilstein 24 III/IV 1875.] |
| 1,3-Dimethylbarbituric acid Preparation Products And Raw materials |
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