Other grades of this product :
| Sapacitabine Basic information |
| Product Name: | Sapacitabine | | Synonyms: | N-[1-[(2R,3S,4S,5R)-3-cyano-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2- oxo-pyrimidin-4-yl]hexadecanamide;Sapacitabine;1-(2-C-Cyano-2-deoxy-β-D-arabino-pentofuranosyl)cytosine;1-(2-Deoxy-2-cyano-β-D-arabinofuranosyl)cytosine;4-Amino-1-[(3β-cyano-4α-hydroxy-5β-hydroxymethyltetrahydrofuran)-2β-yl]pyrimidin-2(1H)-one;CNDAC;1-(2-cyano-2-deoxy-β-D-arabinofuranosyl)-4-(palMitoylaMino)pyriMidin-2(1H)-one,Sapacitabine;2'-cyano-2'-deoxy-N4-palMitoyl-1-β-D-arabinofuranosyl-cytosine, sapacitabine, CYC682 | | CAS: | 151823-14-2 | | MF: | C26H42N4O5 | | MW: | 490.64 | | EINECS: | | Product Categories: | | Mol File: | 151823-14-2.mol |
| Sapacitabine Chemical Properties |
| Melting point | >177°C (dec.) | | density | 1.21±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer, Under inert atmosphere | | solubility | DMSO (Slightly), Methanol (Slightly, Heated) | | pka | 10.04±0.20(Predicted) | | form | Solid | | color | White to Off-White |
| Sapacitabine Usage And Synthesis |
| Uses | Sapacitabine, it is an orally available nucleoside analog prodrug of CNDAC that acts through a dual mechanism. It has potential use in chemotherapy. | | Biochem/physiol Actions | Sapacitabine is an orally active prodrug of nucleoside analog CNDAC that exhibits potent anti-tumor activity in both blood and solid tumors. CNDAC incorporates into DNA where it causes single-strand breaks (SSBs), which are converted into double strand breaks (DSBs) during S phase. |
| Sapacitabine Preparation Products And Raw materials |
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