Other grades of this product :
| PHOSPHODIESTERASE II Basic information |
| Product Name: | PHOSPHODIESTERASE II | | Synonyms: | 3'-EXONUCLEASE TYPE I-SA;SPLEEN EXONUCLEASE;SPLEEN PHOSPHODIESTERASE TYPE I-SA;PDEII;PHOSPHODIESTERASE, TYPE II, CALF SPLEEN;PHOSPHODIESTERASE II;PHOSPHODIESTERASE, TYPE II;PHOSPHODIESTERASE II TYPE I-SA | | CAS: | 9068-54-6 | | MF: | | MW: | 0 | | EINECS: | 232-965-0 | | Product Categories: | | Mol File: | Mol File |
| PHOSPHODIESTERASE II Chemical Properties |
| storage temp. | -20°C | | form | lyophilized powder |
| PHOSPHODIESTERASE II Usage And Synthesis |
| Uses | The product has been used in the characterization of polynucleotide chain length, base composition, and identity of terminal nucleotide. The enzyme has also been used in excision of pyridyloxobutyl (POB) base adducts from DNA. Furthermore, it has been used along with micrococcal endonuclease to hydrolyze purified DNA to 3 -nucleoside monophosphates. | | General Description | Phosphodiesterase (PDE) II belong to the PDE superfamily and includes subtypes from one to 11. They exists as a dimer and comprise a N-terminal regulatory domain, C-terminal prenylated domain and a Zn2+ containing catalytic domain. The bovine spleen PDE2 corresponds to a molecular weight of 65 kDa. It requires divalent cations for its enzymatic activity and has an optimum pH of 7.5. | | Biochem/physiol Actions | Phosphodiesterase (PDE) breaks phosphodiester bonds. 3-Isobutyl-methylxanthine (IBMX) is a potential PDE2 inhibitor. |
| PHOSPHODIESTERASE II Preparation Products And Raw materials |
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