Trigonelline hydrochloride

Trigonelline hydrochloride
  • CAS No.:6138-41-6
Other grades of this product :
Trigonelline hydrochloride Basic information
Product Name:Trigonelline hydrochloride
Synonyms:1-METHYLPYRIDINIUM-3-CARBOXYLATE HYDROCHLORIDE;N-METHYLNICOTINIC ACID BETAINE HYDROCHLORIDE;TRIGONELLIN HYDROCHLORIDE;TRIGONELLINE HYDROCHLORIDE;TRIGONELLINE HCL;TIMTEC-BB SBB000182;3-carboxy-1-methylpyridinium chloride;EINECS 228-119-5
CAS:6138-41-6
MF:C7H8ClNO2
MW:173.6
EINECS:228-119-5
Product Categories:chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors;Alkaloids;Biochemistry;Pyridine Alkaloids;Pyridinium Compounds
Mol File:6138-41-6.mol
Trigonelline hydrochloride Chemical Properties
Melting point ~260 °C (dec.)
storage temp. Inert atmosphere,Room Temperature
solubility Methanol (Slightly), Water
form neat
color White to Off-White
Merck 14,9694
BRN 3734169
CAS DataBase Reference6138-41-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-36-26
WGK Germany 3
HS Code 29333990
MSDS Information
ProviderLanguage
SigmaAldrich English
Trigonelline hydrochloride Usage And Synthesis
DescriptionTrigonelline hydrochloride (N-methylnicotinic acid betaine hydrochloride) is a betaine type pyrimidine alkaloid found in various seeds, including coffee beans. Trigonelline is synthesized from nicotinic acid in many plant species. It has been reported that trigonelline has diverse biological activities, such as hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and anti-tumor activities. (The product is for research purpose only.)
UsesTrigonelline (chloride) is an alkaloid found in plants and coffee. Trigonelline is a product of niacin metabolism that is excreted in urine.
ReferencesTrigonelline: a plant alkaloid with therapeutic potential for diabetes and central nervous system disease (a review)J. Zhou, L. Chan, S. Zhou, Curr. Med. Chem. 2012, 19, 3523.A Review on Biosynthesis, Analytical Techniques, and Pharmacological Activities of Trigonelline as a Plant AlkaloidN. Mohamadi, F. Sharififar, M. Pournamdari, M. Ansari, J. Dietary Suppl. 2018, 15, 207.
Trigonelline hydrochloride Preparation Products And Raw materials
Preparation ProductsPyridine

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