3-(trifluoromethyl)pyridin-2-ol

CAS No.：22245-83-6

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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2-Hydroxy-3-trifluoromethylpyridine Basic information

Product Name:	2-Hydroxy-3-trifluoromethylpyridine
Synonyms:	2-HYDROXY-3-(TRIFLUOROMETHYL)PYRIDINE;3-(TRIFLUOROMETHYL)-1,2-DIHYDROPYRIDIN-2-ONE;3-(TRIFLUOROMETHYL)-2-PYRIDONE;BUTTPARK 24\01-66;3-(Trifluoromethyl)pyridin-2-one;3-Trifluoromethyl-pyridin-2-ol;2-Hydroxy-3-(trifluoromethyl)pyridine 97%;2-Hydroxy-3-(trifluoromethyl)pyridine97%
CAS:	22245-83-6
MF:	C6H4F3NO
MW:	163.1
EINECS:	671-273-7
Product Categories:	Fluorine series;blocks;FluoroCompounds;Pyridines;Pyridine
Mol File:	22245-83-6.mol

2-Hydroxy-3-trifluoromethylpyridine Chemical Properties

Melting point	150-153°C
Boiling point	223.7±40.0 °C(Predicted)
density	1.398±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
form	powder to crystal
pka	9.67±0.10(Predicted)
color	White to Almost white
LogP	0.71 at 25℃
CAS DataBase Reference	22245-83-6(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,Xn,T
Risk Statements	36/37/38-65-20/21/22-20/21-36-25
Safety Statements	26-36/37/39-36-45
RIDADR	UN2811
HazardClass	IRRITANT
HS Code	29333990

MSDS Information

2-Hydroxy-3-trifluoromethylpyridine Usage And Synthesis

Chemical Properties	White powder
Uses	2-Hydroxy-3-trifluoromethylpyridine is a reactant in the synthesis of Pyrido[2,3-b]pyrazine, a TRPV1 antagonist .

2-Hydroxy-3-trifluoromethylpyridine Preparation Products And Raw materials

Preparation Products

5-isothiocyanato-3-(trifluoromethyl)picolinonitrile-->5-IODO-3-(TRIFLUOROMETHYL)-2(1H)-PYRIDINONE-->2-CHLORO-5-NITRO-3-(TRIFLUOROMETHYL)PYRIDINE

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