2-Thiophenemethanol

CAS No.：636-72-6

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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2-Thiophenemethanol Basic information

Product Name:	2-Thiophenemethanol
Synonyms:	2-THENYL ALCOHOL;2-THIENYL CARBINOL;2-THIENYLETHANOL;2-THIENYLMETHANOL;2-THIOPHENEMETHANOL;2-THIOPHENETHANOL;2-THIOPHENECARBINOL;2-(2-HYDROXYETHYL)THIOPHENE
CAS:	636-72-6
MF:	C5H6OS
MW:	114.17
EINECS:	211-264-3
Product Categories:	Building Blocks;C4 to C6;Sulphur Derivatives;Chemical Synthesis;Heterocyclic Building Blocks;Thiophenes;Thiophene&Benzothiophene;Alkohols;Heterocyclic Compounds
Mol File:	636-72-6.mol

2-Thiophenemethanol Chemical Properties

Melting point	0°C
Boiling point	207 °C (lit.)
density	1.205 g/mL at 25 °C (lit.)
refractive index	n20/D 1.564(lit.)
FEMA	4642 \| 2-THIENYLMETHANOL
Fp	214 °F
storage temp.	2-8°C
form	Liquid
pka	13.89±0.10(Predicted)
color	Clear colorless to light yellow
Water Solubility	40 g/L (20 ºC)
Sensitive	Air Sensitive
JECFA Number	2111
BRN	383595
CAS DataBase Reference	636-72-6(CAS DataBase Reference)
NIST Chemistry Reference	2-Thiophenemethanol(636-72-6)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	23-24/25-36-26
WGK Germany	3
F	13
HS Code	29349990

MSDS Information

Provider	Language
Thiophene-2-methanol	English
SigmaAldrich	English
ACROS	English
ALFA	English

2-Thiophenemethanol Usage And Synthesis

Chemical Properties	clear colourless to light yellow liquid
Uses	No commercially developed applications.
Uses	2-?Thiophenemethanol is a heterocyclic building block used in pharmaceutical and organic synthesis. It is a component of the synthesis of styrylheterocycle analogs of reservatrol which act as apoptosis-inducing agents. Also used in the preparation of diverse 2-aminothiophenes displaying biologically active antiproliferative activity.

2-Thiophenemethanol Preparation Products And Raw materials

Raw materials	(ACETYLOXY)(2-THIENYL)METHYL ACETATE-->(5-BROMOTHIEN-2-YL)METHANOL-->(4-BROMO-2-THIENYL)METHANOL-->2-Thiophenecarboxylic acid-->Ethyl 2-thiophenecarboxylate-->2-Iodothiophene
Preparation Products	2-(Chloromethyl)thiophene-->2-Thenaldehyde-->2-Methylthiophene-->5-BROMO-2,2'-BITHIOPHENE-5'-CARBOXALDEHYDE-->BETA-(2-THIENYL)-DL-ALANINE-->2-Thienylmethanethiol-->D-2-THIENYLALANINE-->tioxazafen-->TRANS-2-PENTEN-1-OL

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