| 4-Phenylpiperidine Basic information |
| Product Name: | 4-Phenylpiperidine |
| Synonyms: | Piperidine, 4-phenyl-;RARECHEM AH CK 0160;LABOTEST-BB LT00233204;LABOTEST-BB LTBB000705;AKOS BBS-00003581;TIMTEC-BB SBB003943;4-Phenylpiperidine 97%;4-PHENYLPIPERDINE |
| CAS: | 771-99-3 |
| MF: | C11H15N |
| MW: | 161.24 |
| EINECS: | 212-243-1 |
| Product Categories: | Building Blocks;Heterocyclic Building Blocks;Piperidines, Piperidones, Piperazines;Piperidine;API intermediates;Piperidines;Amines and Anilines;PYRIDINE |
| Mol File: | 771-99-3.mol |
| 4-Phenylpiperidine Chemical Properties |
| Melting point | 61-65 °C (lit.) |
| Boiling point | 286 °C(lit.) |
| density | 1.062 g/mL at 25 °C(lit.) |
| refractive index | n |
| Fp | >230 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | Powder |
| pka | 10.20±0.10(Predicted) |
| color | Yellow to brown |
| Water Solubility | Soluble in water. |
| BRN | 124508 |
| CAS DataBase Reference | 771-99-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 4-Phenylpiperidine(771-99-3) |
| Safety Information |
| Hazard Codes | T,Xi,C,F |
| Risk Statements | 36/37/38-34-11-20/21/22 |
| Safety Statements | 26-36/37/39-45-37/39-36/37-16 |
| RIDADR | UN 2922 8/PG 2 |
| WGK Germany | 3 |
| RTECS | TM2625000 |
| F | 10 |
| HazardClass | IRRITANT |
| HS Code | 29333990 |
| MSDS Information |
| Provider | Language |
|---|---|
| 4-Phenylpiperidine | English |
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| 4-Phenylpiperidine Usage And Synthesis |
| Chemical Properties | off-white to light brown crystalline powder and/or |
| Uses | 4-Phenylpiperidine is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff. |
| Definition | 4-Phenylpiperidine is a benzene ring bound to a piperidine ring. It is the base structure for a variety of opioids, such as pethidine (meperidine), ketobemidone, alvimopan, loperamide, and diphenoxylate. |
| 4-Phenylpiperidine Preparation Products And Raw materials |
| Raw materials | Thionyl chloride-->Toluene-->Potassium hydroxide-->Sodium amide-->Phenylacetylene-->Bis(2-ethylhexyl)amine |
| Preparation Products | 1,3-DIMETHYL-4-PHENYL-4-PIPERIDINOL-->4-(4'-Bromophenyl)piperidine |
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