4-Bromo-3-(trifluoromethyl)aniline

CAS No.：393-36-2

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4-Bromo-3-(trifluoromethyl)aniline Basic information

Product Name:	4-Bromo-3-(trifluoromethyl)aniline
Synonyms:	4-Bromo-alpha,alpha,alpha-trifluoro-m-toluidine;Benzenamine, 4-bromo-3-(trifluoromethyl)-;5-amino-2-bromo-trifluoromethylbenzene / 4-bromo-3-trifluoromethyl-aniline;4-Bromo-3-(trifluoromethyl)aniline, 4-Bromo-alpha,alpha,alpha-trifluoro-m-toluidine;2-BROMO-5-AMINOBENZOTRIFLUORIDE;4-BROMO-3-(TRIFLUOROMETHYL)ANILINE;4-BROMO-3-TRIFLUOROMETHYL-PHENYLAMINE;4-AMINO-1-BROMO-2-(TRIFLUOROMETHYL)BENZENE
CAS:	393-36-2
MF:	C7H5BrF3N
MW:	240.02
EINECS:	206-885-1
Product Categories:	Miscellaneous;Benzotrifluoride Series;Aniline;C7;Nitrogen Compounds;Aniline series;Trifluoromethylbenzene serise;Amines;blocks;Bromides;Building Blocks;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;amine\| alkyl bromide;bc0001
Mol File:	393-36-2.mol

4-Bromo-3-(trifluoromethyl)aniline Chemical Properties

Melting point	47-49 °C(lit.)
Boiling point	81-84 °C0.5 mm Hg(lit.)
density	1.6925 (rough estimate)
refractive index	1.5320 (estimate)
Fp	>230 °F
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	soluble in Methanol
form	Solid:crystalline
pka	2.67±0.10(Predicted)
color	White to Orange to Green
PH	6.86 at 25℃ and 10g/L
BRN	641589
LogP	2.7 at 30℃
CAS DataBase Reference	393-36-2(CAS DataBase Reference)
NIST Chemistry Reference	5-Amino-2-bromobenzotrifluoride(393-36-2)

Safety Information

Hazard Codes	Xn,Xi
Risk Statements	20/21/22-36/37/38
Safety Statements	26-36
RIDADR	2811
WGK Germany	3
Hazard Note	Irritant
HazardClass	6.1
HS Code	29214300

MSDS Information

Provider	Language
4-Bromo-3-(trifluoromethyl)aniline	English
SigmaAldrich	English
ALFA	English

4-Bromo-3-(trifluoromethyl)aniline Usage And Synthesis

Chemical Properties	White to off-white crystalline
Uses	4-Bromo-3-(trifluoromethyl)aniline has been used in the preparation of: 2,5-dibromo-(trifluoromethyl)benzene and 2-bromo-5-iodo-(trifluoromethyl)benzene AUY954, an aminocarboxylate analog of FTY720, a low nanomolar, monoselective agonist of the sphingosine-1-phosphate receptor

4-Bromo-3-(trifluoromethyl)aniline Preparation Products And Raw materials

Raw materials	2-Bromo-5-nitrobenzotrifluoride-->4-BROMO-3-(TRIFLUOROMETHYL)ACETANILIDE-->2-Bromobenzotrifluoride-->3-(TRIFLUOROMETHYL)ACETANILIDE-->3-Aminobenzotrifluoride-->2-Aminobenzotrifluoride
Preparation Products	2-Bromo-5-(trifluoromethyl)aniline-->2-bromo-3-(trifluoromethyl)aniline-->4-BROMO-3-TRIFLUOROMETHYL-BENZALDEHYDE-->3-Trifluoromethyl-4-bromobenzonitrile

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