5-[Bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester

CAS No.：3543-74-6

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5-[Bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester Basic information

Product Name:	5-[Bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester
Synonyms:	Ethyl-4-(5-(bis(2-hydroxyethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanoate;5-[Bis(2-hydroxyethyl)aMino]-1-Methyl-2-benziMidazolebutyric Acid Ethyl Ester;4-[5-[Bis(2-hydroxyethyl)aMino]-1-MethylbenziMidazol-2-yl]butanoic acid ethyl ester;ethyl 4-{5-[bis(2-hydroxyethyl)aMino]-1-Methyl-1H-1,3-benzodiazol-2-yl}butanoate;Bendamustine Related Impurity 1;1H-Benzimidazole-2-butanoicacid, 5-[bis(2-hydroxyethyl)amino]-1-methyl-, ethyl ester;5-[Bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester;4-{5-[Bis-(2-hydroxy-ethyl)-amino]-1-methyl-1H-benzoimidazol-2-yl}-butyric acidethylester
CAS:	3543-74-6
MF:	C18H27N3O4
MW:	349.42
EINECS:	680-672-5
Product Categories:	intermediate;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:	3543-74-6.mol

5-[Bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester Chemical Properties

Melting point	98-101°C
Boiling point	580.6±50.0 °C(Predicted)
density	1.21±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Store in freezer, under -20°C
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	14.26±0.10(Predicted)
color	White to Brown

Safety Information

HS Code

2933998350

MSDS Information

5-[Bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester Usage And Synthesis

Chemical Properties	Off-White to Light Tan Solid
Uses	[1-Methyl-5-bis(2’-hydroxyethyl)aminobenzimidazolyl-2]butanoic Acid Ethyl Ester_x000D_Bendamustine Related Impurity 1 (cas# 3543-74-6) is a compound useful in organic synthesis.

5-[Bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester Preparation Products And Raw materials

Raw materials

2,2'-[[4-(methylamino)-3-nitrophenyl]imino]bisethanol-->1H-Benzimidazole-2-butanoic acid, 5-[bis(2-hydroxyethyl)amino]-2,3-dihydro-2-hydroxy-1-methyl--->oxirene-->4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid-->NA-->2-Fluoro-5-nitroaniline-->1-Methyl-5-amino-1H-benzimidazole-2-butanoic acid ethyl ester-->1-Methyl-5-nitro-2-benzimidazolebutyric acid-->2,2'-[(4-fluoro-3-nitrophenyl)imino]bisethanol-->ethyl 4-(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoate-->ETHYLENE OXIDE-->2-Bromoethanol-->Ethanol

Preparation Products

Bendamustine hydrochloride

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