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| VUF 10166 Basic information |
| Product Name: | VUF 10166 | | Synonyms: | 2-Chloro-3-(4-Methyl-1-piperazinyl)quinoxaline;VUF 10166;Quinoxaline, 2-chloro-3-(4-methyl-1-piperazinyl)-;2-chloro-3-(4-methylpiperazin-1-yl)quinoxaline;VUF 10166 USP/EP/BP | | CAS: | 155584-74-0 | | MF: | C13H15ClN4 | | MW: | 262.74 | | EINECS: | | Product Categories: | Inhibitors | | Mol File: | 155584-74-0.mol |
| VUF 10166 Chemical Properties |
| Boiling point | 389.6±42.0 °C(Predicted) | | density | 1.279±0.06 g/cm3(Predicted) | | solubility | ≥26.3 mg/mL in EtOH; insoluble in H2O; ≥38.8 mg/mL in DMSO | | form | solid | | pka | 6.55±0.42(Predicted) |
| VUF 10166 Usage And Synthesis |
| Uses | VUF 10166 is a 5-HT3 receptor antagonist. VUF 10166 exhibits partial agonist activity at 5-HT3A receptors at higher concentrations. VUF 10166 is also histamine H4 receptor antagonist. | | Uses | VUF 10166 is a 5-HT3 receptor antagonist. VUF 10166 exhibits partial agonist activity at 5-HT3A receptors at higher concentrations. VUF 10166 is also histamine H4 receptor antagonist. | | Biological Activity | vuf10166 is a novel, potent and competitive antagonist for 5-ht3a receptor with ki of 0.04 nm, its affinity at 5-ht3ab receptor is significantly lower. |
| VUF 10166 Preparation Products And Raw materials |
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