7-(Diethylamino)coumarin-3-carboxylic acid

7-(Diethylamino)coumarin-3-carboxylic acid
  • CAS No.:50995-74-9
Other grades of this product :
7-(Diethylamino)coumarin-3-carboxylic acid Basic information
Product Name:7-(Diethylamino)coumarin-3-carboxylic acid
Synonyms:DEAC ACID;RARECHEM AB KA K024;7-(DIETHYLAMINO)COUMARIN-3-CARBOXYLIC AC ID, FOR FLUORESC.;7-DIETHYLAMINOCOUMARIN-3-CARBOXYLIC ACID;7-(DIETHYLAMINO)-2-OXO-2H-CHROMENE-3-CARBOXYLIC ACID;7-(Diethylamino)-2-oxo-2H-chromene-3-carboxylic acid, 7-(Diethylamino)-2-oxo-2H-1-benzopyran-3-carboxylic acid;7ACC 1;7ACC1
CAS:50995-74-9
MF:C14H15NO4
MW:261.27
EINECS:
Product Categories:DetectionFluorescent Indicators and Probes;Fluorescent Labels;Fluorescent Probes, Labels, Particles and Stains;Functional Group Reactive Labels;Functional Group Reactive Labels for SpectroscopyFluorescent Probes, Labels, Particles and Stains;Lipophilic and Membrane Probes;Dialkylcarbocyanine and Styryl probesFluorescent Probes, Labels, Particles and Stains;Biochemicals and Reagents;Other Fluorescent Labels
Mol File:50995-74-9.mol
7-(Diethylamino)coumarin-3-carboxylic acid Chemical Properties
Melting point 222-224 °C (dec.)(lit.)
Boiling point 464.7±45.0 °C(Predicted)
density 1.317±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMF: soluble
pka-98.36 ± 0.20, most acidic, temperature: 25 °C; 6.06 ± 0.20, most basic(at 25℃)
form Solid
color Bright orange solid; Orange crystals; Orange crystalline solid; Orange laths; Orange powder; Orange solid
λmax409 nm (Buffer pH 9.0)
BRN 6145963
Major ApplicationEpoxy resinsphotoluminescent devices;lithographic platematerials; oil-repellent copolymers/coatings;polymer matrices; silica nanoparticles for imaging,security, and sensing applications
Biological ApplicationsDetecting hydrogenperoxide; evaluating iron ions; cysteine cathepsinsinhibitors; β-glucosidase inhibitors; humanmonoamine oxidase inhibitors; N-Methyl-D-aspartatereceptors (NMDARs) inhibitors; phosphateassay; probing actomyosin mechanism;treatingcancer/antitumor activity,treating cognitive deficits orschizophrenia;as a substrate for measuring proteinkinase activity
Safety Information
Hazard Codes Xi
Safety Statements 22-24/25
WGK Germany 3
8-10
Hazard Note Irritant
HS Code 29322090
MSDS Information
ProviderLanguage
SigmaAldrich English
7-(Diethylamino)coumarin-3-carboxylic acid Usage And Synthesis
Uses7-(Diethylamino)-coumarin-3-carboxylic acid is a reagent for the derivatisation of amines and proteins. It has also been used for labelling synthetic peptides for high-throughput detection.
Uses7-(Diethylamino)coumarin-3-carboxylic acid is an amine-reactive fluorescent label used for protein conjugation.
7-(Diethylamino)coumarin-3-carboxylic acid Preparation Products And Raw materials
Preparation Products7-(diethylaMino)-2-oxo-2H-chroMene-3-carbaldehyde

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