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| Pyrrole-2-carboxylic acid Basic information |
| Pyrrole-2-carboxylic acid Chemical Properties |
| Melting point | 204-208 °C (dec.) (lit.) | | Boiling point | 340.3±15.0 °C(Predicted) | | density | 0.862 | | refractive index | 1.441-1.445 | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Soluble in methanol. | | form | Powder | | pka | 4.45(at 20℃) | | color | White to off-white to pale pink | | BRN | 80825 | | CAS DataBase Reference | 634-97-9(CAS DataBase Reference) | | NIST Chemistry Reference | Pyrrole-2-carboxylic acid(634-97-9) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36-37/39 | | WGK Germany | 3 | | Hazard Note | Irritant | | HS Code | 29339900 |
| Pyrrole-2-carboxylic acid Usage And Synthesis |
| Chemical Properties | Light brown powder | | Uses | Pyrrole-2-carboxylic acid is small amphoteric polar metabolite produced by many Streptomyces species, often co-produced with its dimer, pyrocoll. Pyrrole-2-carboxylic acid is an important dereplication standard in discovery, displaying a distinctive UV spectrum and a broad range of biological activities, albeit weak. More recently, pyrrole-2-carboxylic has demonstrated antiparasitic activity against Trypanosomes by selective proline racemase inhibition and has potent antifungal activity against Phytophthora. | | Uses | Pyrrole-2-carboxylic Acid is a reagent used in the synthesis of potent small molecule inhibitors of severe acute respiratory syndrome (SARS) coronavirus. Also used in the synthesis of [2,3-c]pyridine-7-one scaffolds. | | Definition | ChEBI: A pyrrolecarboxylic acid that is 1H-pyrrole carrying a carboxy substituent at position 2. |
| Pyrrole-2-carboxylic acid Preparation Products And Raw materials |
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