Product

4-(Aminomethyl)tetrahydro-2H-pyran

CAS No.：130290-79-8

Other grades of this product :

4-(Aminomethyl)tetrahydro-2H-pyran Basic information

Product Name:	4-(Aminomethyl)tetrahydro-2H-pyran
Synonyms:	C-(TETRAHYDRO-PYRAN-4-YL)-METHYLAMINE;ASINEX-REAG BAS 07731534;1-TETRAHYDRO-2H-PYRAN-4-YLMETHANAMINE;4-AMINOMETHYLTETRAHYDROPYRAN;4-(Aminomethyl)tetrahydro-2H-pyran 98%;(TETRAHYDROPYRAN-4-YL)METHYLAMINE;(TETRAHYDRO-2H-PYRAN-4-YL) METHANAMINE;(TETRAHYDRO-2H-PYRAN-4-YLMETHYL)AMINE
CAS:	130290-79-8
MF:	C6H13NO
MW:	115.17
EINECS:	638-888-2
Product Categories:	Aminomethyl's;Pyrans, Piperidines & Piperazines;Amines;blocks;Heterocycles
Mol File:	130290-79-8.mol

4-(Aminomethyl)tetrahydro-2H-pyran Chemical Properties

Boiling point	75 °C
density	1.02
refractive index	1.4630-1.4670
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
form	clear liquid
pka	10.01±0.29(Predicted)
color	Colorless to Light yellow
CAS DataBase Reference	130290-79-8(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,C,Xn
Risk Statements	34-41-37/38-22
Safety Statements	26-36/37/39-45-39
RIDADR	2735
HazardClass	IRRITANT
PackingGroup	Ⅲ
HS Code	29329990

MSDS Information

4-(Aminomethyl)tetrahydro-2H-pyran Usage And Synthesis

Chemical Properties	clear colorless liquid
Uses	4-Aminomethyltetrahydropyran is a reagent that is used in core modification in discovery of CC214-2 which is an orally available , selective inhibitor of mTOR kinase. 4-Aminomethyltetrahydropyran is also used as a reagent in the development of pyrazoloquinolines as PDE10A inhibitor for the treatment of schizophrenia.

4-(Aminomethyl)tetrahydro-2H-pyran Preparation Products And Raw materials

Raw materials

Ethanol-->Hydrochloric acid-->Ethyl acetate-->Tetrahydrofuran-->Sodium-->Potassium carbonate-->Potassium hydroxide-->Ammonium hydroxide-->Acetone-->Hexane-->Lithium Aluminum Hydride-->Dimethyl sulfate-->Diethyl malonate-->Ethyl propionate-->2,2'-Dichlorodiethyl ether-->methyl 4-cyanotetrahydro-2H-pyran-4-carboxylate-->TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE-->Tetrahydropyranyl-4-acetic acid

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