| 2,3,5-Triphenyltetrazolium chloride Basic information |
| Product Name: | 2,3,5-Triphenyltetrazolium chloride |
| Synonyms: | 2,3,5-TriphenyltetrazoliuM chloride SynonyMs 2,3,5-Triphenyl-2H-tetrazoliuM chloride;TTC,TTZ,Tetrazolium Red;FLJ37239;LGMD2K;10 MG ABTS TABLETS;BCIP P-TOLUIDINE SALT ULTRA PURE GRADE;TSA PENASE CONTACT 55MM TRIPLE-WRAP;red tetazolium |
| CAS: | 298-96-4 |
| MF: | C19H15ClN4 |
| MW: | 334.8 |
| EINECS: | 206-071-6 |
| Product Categories: | substrate;Tetrazolium Salts;Tetrazolium Salts & Formazans;Tetrazolium salt |
| Mol File: | 298-96-4.mol |
| 2,3,5-Triphenyltetrazolium chloride Chemical Properties |
| Melting point | 250 °C(lit.) |
| Boiling point | 490.96°C (rough estimate) |
| density | 1.1704 (rough estimate) |
| refractive index | 1.6110 (estimate) |
| storage temp. | 2-8°C |
| solubility | H2O: may be clear to slightly hazy |
| form | powder |
| color | faint yellow |
| Water Solubility | Soluble in water, ethanol and acetone. Insoluble in ether. |
| λmax | 247 nm |
| Sensitive | Light Sensitive & Hygroscopic |
| Merck | 14,9744 |
| BRN | 3923356 |
| Stability: | Stable. Light sensitive. Protect from moisture. Incompatible with strong oxidizing agents. |
| Biological Applications | Algae viability assay; microbial growth assays; transketolase activity screening assays; detecting bacteria,g-hydroxybutyric acid (GHB),microorganisms,myocardial infarction; measuring dehydrogenase activity; treating cancer |
| InChIKey | PKDBCJSWQUOKDO-UHFFFAOYSA-M |
| CAS DataBase Reference | 298-96-4(CAS DataBase Reference) |
| EPA Substance Registry System | 2,3,5-Triphenyltetrazolium chloride (298-96-4) |
| Safety Information |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-20/21/22 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| RTECS | XF8100000 |
| F | 3-8-10 |
| TSCA | Yes |
| HS Code | 29339900 |
| Toxicity | LD50 intravenous in mouse: 5600ug/kg |
| MSDS Information |
| Provider | Language |
|---|---|
| 2,3,5-Triphenyl-2H-tetrazolium chloride | English |
| SigmaAldrich | English |
| ALFA | English |
| 2,3,5-Triphenyltetrazolium chloride Usage And Synthesis |
| Chemical Properties | white powder |
| Uses | 2,3,5-Triphenyl-2H-tetrazolium chloride is used as a dye in cell biological studies. |
| Uses | 2,3,5-Triphenyltetrazolium chloride is a selective serotonin 5-HT4 receptor agonist and 5-HT3 gastrointestinal prokinetic agent for functional dyspepsia |
| Uses | In analytical chemistry as a sensitive reagent for reducing sugars, and to distinguish between a-ketols and simple aldehydes. For staining plant and animal tissue. Germination indicator in testing the ability of seeds to germinate: G. Lakon, Ber. Dtsch. Bot. Ges. 60, 299, 434 (1942). In histochemical studies. In determination of antibiotics; of dehydrogenases. |
| Definition | ChEBI: An organic chloride salt having 2,3,5-triphenyltetrazolium as the counterion. |
| General Description | 2,3,5-Triphenyltetrazolium chloride is a colorless water-soluble dye. In the mitochondria of living cells, it is reduced to a deep red, water-insoluble compound (formazan). 2,3,5-Triphenyltetrazolium chloride helps to distinguish between viable and infarcted brain tissue after stroke. |
| Purification Methods | Crystallise TTZ from EtOH or CHCl3, and dry it at 105o. [Beilstein 26 H 363, 26 II 216, 26 III/IV 1774.] |
| 2,3,5-Triphenyltetrazolium chloride Preparation Products And Raw materials |
| Raw materials | Sodium hydroxide-->Hydrochloric acid-->Acetic acid-->Sodium nitrite-->Sodium acetate-->Aniline-->Sodium hypochlorite-->Benzaldehyde-->Phenylhydrazine |
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