Other grades of this product :
| 1-(2-Methoxyphenyl)piperazine Basic information |
| 1-(2-Methoxyphenyl)piperazine Chemical Properties |
| Melting point | 35-40 °C (lit.) | | Boiling point | 130-133 °C/0.1 mmHg (lit.) | | density | 1.095 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.575(lit.) | | Fp | >230 °F | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | form | Liquid After Melting | | pka | 8.98±0.10(Predicted) | | color | Clear colorless to yellow | | Water Solubility | Soluble in chloroform, ethyl acetate, and methanol. Insoluble in water | | Sensitive | Air Sensitive | | BRN | 167888 | | LogP | 1.67 | | CAS DataBase Reference | 35386-24-4(CAS DataBase Reference) |
| 1-(2-Methoxyphenyl)piperazine Usage And Synthesis |
| Chemical Properties | clear colorless to yellow liquid after melting | | Uses | A piperazine derivative and a selective antagonist at D3 receptors that influences the expression of cocaine-induced conditioned place preference (CPP). | | Uses | It is used as pharmaceutical intermediate. N-alkylated 1-(2-methyoxyphenyl)piperazines markedly improved affinity and selectivity of the dopamine D3 receptor which is recognized as a potential therapeutic target for the treatment of various neurological and psychiatric disorders. | | Uses | 1-(2-Methoxyphenyl)piperazine can be used:- To functionalize pyrazolylvinyl ketones via Aza-Michael addition reaction.
- To prepare cyclic amine substituted Tr?ger′s base derivatives.
- To prepare functionalized bis(mercaptoimidazolyl)borates by reacting with the activated ester, [(1-methyl-2-mercaptoimidazol-5-yl)carbonyl]succinimide.
|
| 1-(2-Methoxyphenyl)piperazine Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye