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| 4-Fluorophenol Basic information |
| 4-Fluorophenol Chemical Properties |
| Melting point | 43-46 °C (lit.) | | Boiling point | 185 °C (lit.) | | density | 1.22 | | Fp | 155 °F | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | 80g/l | | form | Crystalline Solid | | pka | 9.89(at 25℃) | | color | Yellow-beige to pink | | PH | 5.4 (H2O, 20℃)(saturated aqueous solution) | | Water Solubility | 50 g/L | | BRN | 1362752 | | Stability: | Stable. Flammable. Incompatible with strong oxidizing agents. | | Dissociation constant | 0 at 27℃ | | CAS DataBase Reference | 371-41-5(CAS DataBase Reference) | | NIST Chemistry Reference | Phenol, 4-fluoro-(371-41-5) | | EPA Substance Registry System | Phenol, 4-fluoro- (371-41-5) |
| 4-Fluorophenol Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powder | | Uses | Intermediates of Liquid Crystals | | Uses | 4-Fluorophenol is a fluorinated phenolic compound with various applications as an starting reagent for the synthesis of pharmaceutical goods. It is widely used intermediate in the industrial production of pharmaceuticals cisapride and Sabeluzole from Janssen, Sorbinil from Pfizer, Progabide from Synthelabo. | | Definition | ChEBI: 4-fluorophenol is a fluorophenol that is phenol in which the hydrogen para- to the hydroxy group has been replaced by a fluorine. It is a fluorophenol and a member of monofluorobenzenes. | | Preparation | Acetyl hypofluorite also will fluoro-demetallate benzene derivatives, for example mercury derivatives of phenol gave 4-fluorophenol. | | Synthesis Reference(s) | Tetrahedron, 52, p. 23, 1996 DOI: 10.1016/0040-4020(95)00867-8 | | Hazard | Irritant. |
| 4-Fluorophenol Preparation Products And Raw materials |
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