Product

N,N,N',N'-Tetramethyl-O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)uronium tetrafluoroborate

CAS No.：125700-69-8

Other grades of this product :

N,N,N',N'-Tetramethyl-O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)uronium tetrafluoroborate Basic information

Product Name:	N,N,N',N'-Tetramethyl-O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)uronium tetrafluoroborate
Synonyms:	O-(3,4-DIHYDRO-4-OXO-1,2,3-BENZOTRIAZIN- 3-YL)-N,N,;O-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N',N'-tetramethyluronium tetra;O-(3,4-DIHYDRO-4-OXO-1,2,3-BENZOTRIZIN-3-YL)-N,N,N',N'-TETRAMETHYLURONIUMTETRAFLUOROBORATE;TDBTU N,N,N'',N''-TETRAMETHYL-O-(3,4-DIHYDRO-4-OXO-1,2,3-BENZOTRIAZIN-3-YL) URONIUMTETRAFLUOROBORATE;N,N,N'',N''-TETRAMETHYL-O-(3,4-DIHYDRO-4-OXO-1,2,3-BENZOTRIAZIN-3-YL)URONIUM TETRAFLUOROBORATE(TDBTU);2-(3,4-DIHYDRO-4-OXO-1,2,3-BENZOTRIAZIN-3-YL)-N,N,N'',N''-TETRAMETHYLURONIUM TETRAFLUOROBORATE;2-(3,4-DIHYDRO-4-OXO-BENZOTRIAZIN-3-YL)TETRAMETHYLURONIUM TETRAFLUOROBORATE;dihydrooxobenzotriazinyl tetramethyluronium fluoroborate
CAS:	125700-69-8
MF:	C12H16BF4N5O2
MW:	349.09
EINECS:
Product Categories:	Peptide;Peptide Coupling Reagents;Coupling Reagent
Mol File:	125700-69-8.mol

N,N,N',N'-Tetramethyl-O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)uronium tetrafluoroborate Chemical Properties

Melting point	147 °C (dec.)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	acetonitrile: 0.1 g/mL, clear
form	Powder or Solid
color	White to yellow
Sensitive	Moisture & Light Sensitive
CAS DataBase Reference	125700-69-8(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	37-36/37/38
Safety Statements	22-24/25-36-26
RIDADR	UN 1759 8/PG III
WGK Germany	3
F	8-10-21
HazardClass	8
PackingGroup	III
HS Code	29339900

MSDS Information

Provider	Language
SigmaAldrich	English

N,N,N',N'-Tetramethyl-O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)uronium tetrafluoroborate Usage And Synthesis

Chemical Properties

Beige crystalline

Uses

O-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N?,N?-tetramethyluronium tetrafluoroborate (2-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate, TBTU) may be used as coupling reagent in the synthesis of macrocyclic polyamine derivatives with various length of linkers, condensation reagent in the large-scale preparation of the hematoregulatory nonapeptide (Glp-Glu-Asp)2-DAS-(Lys)2 (2,SK&F 107647), coupling reagent for peptide synthesis which best suppresses racemization during fragment condensation.

N,N,N',N'-Tetramethyl-O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)uronium tetrafluoroborate Preparation Products And Raw materials

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