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| Esomeprazole magnesium trihydrate Basic information |
| Product Name: | Esomeprazole magnesium trihydrate | | Synonyms: | ESOMEPRAZOLE MAGNESIUM TRIHYDRATE;bis(5-methoxy-2-[(s)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1h-benzylimidazole-1-yl) magnesium trihydrate;(T-4)-Bis[5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazolato]magnesium;Nexium;ESOPMEPRAZOLE MG TRIHYDRATE;5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]benzimidazol-1-ide;5-methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]benzimidazol-1-ide;5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide | | CAS: | 217087-09-7 | | MF: | C34H38MgN6O7S2 | | MW: | 731.14 | | EINECS: | 669-839-3 | | Product Categories: | Acid pump inhibitors;Chiral Reagents;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 217087-09-7.mol |
| Esomeprazole magnesium trihydrate Chemical Properties |
| Melting point | 184-189°C (dec.) | | storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | | solubility | Slightly soluble in water, soluble in methanol, practically insoluble in heptane. | | form | neat | | InChIKey | VEVZQDGATGBLIC-UHFFFAOYSA-N | | CAS DataBase Reference | 217087-09-7(CAS DataBase Reference) |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | 3 | | HS Code | 2933399090 |
| Esomeprazole magnesium trihydrate Usage And Synthesis |
| Chemical Properties | Off-White Powder | | Uses | S-Form of Omeprazole. Gastric proton-pump inhibitor | | Uses | esomeprazole magnesium trihydrate for the healing of peptic ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy.
- Zollinger-Ellison syndrome
- Peptic ulcer, site unspecified
- Duodenal ulcer
- Gastric ulcer
- Gastro-oesophageal reflux disease
Esomeprazole belongs to the family of medications known as proton pump inhibitors (PPIs). Esomeprazole is registered by the Therapeutic Goods Administration (TGA) for the following indications:
- Gastro-Oesophageal Reflux Disease (GORD):
- treatment of erosive reflux oesophagitis;
- long-term management of patients with healed oesophagitis to prevent relapse;
- symptomatic treatment of gastro-oesophageal reflux disease (GORD).
In combination with appropriate antibiotics for:
- healing of duodenal ulcer associated with Helicobacter pylori;
- eradication of Helicobacter pylori in patients with active or healed peptic ulcer.
- Short-term treatment of upper gastrointestinal symptoms associated with non-steroidal anti-inflammatory drug (NSAID) (non-selective and COX-2 selective) therapy.
- Healing of gastric ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy.
- Prevention of gastric and duodenal ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy in patients at risk.
| | Uses | Esomeprazole Magnesium Trihydrate is used in preparation of esomeprazole magnesium trihydrate. | | Brand name | Nexium (AstraZeneca). |
| Esomeprazole magnesium trihydrate Preparation Products And Raw materials |
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