4-Hydroxybenzhydrazide

CAS No.：5351-23-5

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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4-Hydroxybenzhydrazide Basic information

Product Name:	4-Hydroxybenzhydrazide
Synonyms:	4-HYDROXYBENZOIC ACID HYDRAZIDE;4-HYDROXYBENZOHYDRAZIDE;4-HYDROXYBENZHYDRAZIDE;AKOS BBS-00008116;4-Hydroxybenzhydrazide, 98+%;PAHBAH;p-hydroxybenzonic acide hydrazidde;4-HYDROXYBENZHYDRAZIDE, FOR FLUORESCENCE
CAS:	5351-23-5
MF:	C7H8N2O2
MW:	152.15
EINECS:	226-326-5
Product Categories:	Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes;Benzoic acid;Phenols
Mol File:	5351-23-5.mol

4-Hydroxybenzhydrazide Chemical Properties

Melting point	264-266 °C (dec.)(lit.)
Boiling point	274.61°C (rough estimate)
density	1.2804 (rough estimate)
refractive index	1.5200 (estimate)
storage temp.	Store at +15°C to +25°C.
solubility	26.5g/l
form	Fine Crystalline Powder
pka	8.57±0.15(Predicted)
color	White to slightly beige
λmax	245nm(MeOH)(lit.)
BRN	473052
CAS DataBase Reference	5351-23-5(CAS DataBase Reference)
NIST Chemistry Reference	P-hydroxybenzoic acid, hydrazide(5351-23-5)

Safety Information

Hazard Codes	Xi,C
Risk Statements	36/37/38
Safety Statements	26-36-37/39
WGK Germany	3
HazardClass	IRRITANT
HS Code	29280090

MSDS Information

Provider	Language
4-Hydroxybenzoic acid hydrazide	English
ACROS	English
SigmaAldrich	English
ALFA	English

4-Hydroxybenzhydrazide Usage And Synthesis

Chemical Properties	white to slightly beige fine crystalline powder
Uses	4-Hydroxybenzhydrazide is a reagent for the rapid automated determination of serum glucose.It can be used as an indicator for the determination of carbohydrates. The acid-hydrolyzable side chains of tissue (liver) bound 4-Hydroxybenzhydrazide can be used as markers to monitor its residues in chickens.
Uses	4-Hydroxybenzhydrazide has been used:for determining the concentration of maltose from starch digestionfor analysis of sugars from fructan containing food hydrolysatein colorimetric assay for reducing sugar estimation from processed feedstuff
Biochem/physiol Actions	4-Hydroxybenzhydrazide (PAHBAH), is used for assaying α-amylase and glucoamylase activities. The assay based on PAHBAH measures non-specifically the free reducing sugar groups present in samples at 415nm colorimetrically.

4-Hydroxybenzhydrazide Preparation Products And Raw materials

Raw materials	Benzoyl chloride, 4,4'-[[6-(diethylamino)-1,3,5-triazine-2,4-diyl]bis(oxy)]bis- (9CI)-->Benzoyl chloride, 4-hydroxy- (9CI)-->4-Hydroxybenzoic acid-->Ethanol-->4-Hydroxybenzaldehyde-->Methylparaben-->Ethylparaben
Preparation Products	4,6-dihydrazinyl-N,N-diphenyl-1,3,5-triazin-2-amine-->Daunorubicin hydrochloride

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