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| BIS-Tris Propane Basic information |
| Product Name: | BIS-Tris Propane | | Synonyms: | Bis Tris propane 1,3-Bis[tris(hydroxymethyl)methylamino]propane;bis-tris propane molecular biology*reagent;BIS-Tris Propane, ULTROL Grade;Bistrishydroxymethylmethylaminopropane;2,2'-(propane-1,3-diyldiimino)bis[2-(hydroxymethyl)propane-1,3-diol];BIS-TRIS PROPANE, BIOTECHNOLOGY PERFORMA NCE CERTIFI;BIS-TRIS PROPANE SIGMAULTRA;BIS-TRIS PROPANE | | CAS: | 64431-96-5 | | MF: | C11H26N2O6 | | MW: | 282.33 | | EINECS: | 264-899-3 | | Product Categories: | Amines;Buffer;Pharmaceutical Raw Materials | | Mol File: | 64431-96-5.mol |
| BIS-Tris Propane Chemical Properties |
| Melting point | 164-165 °C(lit.) | | Boiling point | 573.3±50.0 °C(Predicted) | | density | 1.326±0.06 g/cm3(Predicted) | | storage temp. | room temp | | solubility | H2O: 1 M at 20 °C, clear, colorless | | form | Powder/Solid | | color | White | | PH | 9.0-10.1 (20-25℃, 1M in water) | | pka | (1) 6.8, (2) 9.0(at 25℃) | | PH Range | 6.3 - 9.5 | | Water Solubility | Soluble in water. | | BRN | 1786109 | | CAS DataBase Reference | 64431-96-5(CAS DataBase Reference) |
| BIS-Tris Propane Usage And Synthesis |
| Description | BIS-TRIS Propane is Good′s buffer. It acts as ligand and forms series of dinuclear hydroxo complexes with Lanthanides(III) in the pH range 7-9. It is useful for diagnostic assay manufacturing industry. | | Chemical Properties | White powder | | Uses | BIS-TRIS Propane may be used in the following studies:- As buffer to investigate the influence of anions with varying nucleophilic properties on the autoxidation of oxymyoglobin (MbO2).
- Purification of glucose-binding protein from membranes of Sulfolobus solfataricus.
- As buffer during GeO2 mineralisation.
| | Uses | BIS-Tris Propane is a buffer that is useful in the pH 6.3 - 9.5 range. This wide buffering range is due to its two pKa values, 6.8 (pKa1) and 9.0 (pKa2), being so close. Because of the wide buffering range, particularly down to pH 6 - 7, this buffer has been used to enhance the stability or activity of restriction enzymes, compared to Tris buffer (which is a poor buffer below pH 7.5 and has a comparatively large change in pKa with temperature). | | Application | BIS-TRIS Propane may be used in the following studies:As buffer to investigate the influence of anions with varying nucleophilic properties on the autoxidation of oxymyoglobin (MbO2).Purification of glucose-binding protein from membranes of Sulfolobus solfataricus.As buffer during GeO2 mineralisation. | | Precautions | This trihydroxyamine analog, also known as bis-tris propane, presents as a white to almost white crystalline powder. Store in a cool and dark place. 1,3-Bis[tris(hydroxymethyl)methylamino]propane is known to be incompatible with oxidizing agents and should not be handled in their vicinity. |
| BIS-Tris Propane Preparation Products And Raw materials |
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