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| 5-Bromo-thiophene-2-carboxylic acid methyl ester Basic information |
| Product Name: | 5-Bromo-thiophene-2-carboxylic acid methyl ester | | Synonyms: | 5-Bromo-thiophene-2-carboxylic acid methyl ester;Methyl 5-bromo-2-thiophenecarboxylate;5-broMo-;Methyl 2-broMothiophene-5...;Methyl 2-broMothiophene-5-carboxylate;2-Thiophenecarboxylic acid, 5-bromo-, methyl ester;methyl 5-bromothiophene-2-carboxylate;5-bromo-2-thiophenecarboxylic acid methyl ester | | CAS: | 62224-19-5 | | MF: | C6H5BrO2S | | MW: | 221.07 | | EINECS: | | Product Categories: | API intermediates | | Mol File: | 62224-19-5.mol |
| 5-Bromo-thiophene-2-carboxylic acid methyl ester Chemical Properties |
| Melting point | 87-88℃ | | Boiling point | 251.9±20.0 °C(Predicted) | | density | 1.662±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| 5-Bromo-thiophene-2-carboxylic acid methyl ester Usage And Synthesis |
| Uses | Methyl 5-Bromo-2-thiophenecarboxylate is used as a reagent in the synthesis of trisubstituted isoxazole derivatives which are novel nonsteroidal antagonists of Farnesoid X Receptor (FXR). FXR plays an important role in regulation of cholesterol, lipid and glucose metabolism. | | Synthesis Reference(s) | Journal of Medicinal Chemistry, 35, p. 1109, 1992 DOI: 10.1021/jm00084a016 |
| 5-Bromo-thiophene-2-carboxylic acid methyl ester Preparation Products And Raw materials |
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