2-Fluoro-6-methylpyridine

2-Fluoro-6-methylpyridine
  • CAS No.:407-22-7
Other grades of this product :
2-Fluoro-6-methylpyridine Basic information
Product Name:2-Fluoro-6-methylpyridine
Synonyms:6-FLUORO-2-PICOLINE;2-FLUORO-6-METHYLPYRIDINE;2-FLUORO-6-PICOLINE;2-FLUORO-6-METHYLPYRIDINE 98%;2-Fluoro-6-methylpyridine/2-Fluoro-6-Picoline;2-Fluoro-6-methylpyridine98%;Pyridine, 2-fluoro-6-methyl-;6-methyl-2-fluoropyridine
CAS:407-22-7
MF:C6H6FN
MW:111.12
EINECS:206-980-8
Product Categories:Fluorine series;Pyridine;Pyridines, Pyrimidines, Purines and Pteredines;Pyridines;Fluoropyridines;Halopyridines;Fluorin-contained pyridine series
Mol File:407-22-7.mol
2-Fluoro-6-methylpyridine Chemical Properties
Boiling point 140-141 °C (lit.)
density 1.077 g/mL at 25 °C (lit.)
refractive index n20/D 1.47(lit.)
Fp 152 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka0.29±0.10(Predicted)
form clear liquid
color Colorless to Light orange to Yellow
Specific Gravity1.07
BRN 107084
InChIKeyUDMNVTJFUISBFD-UHFFFAOYSA-N
CAS DataBase Reference407-22-7(CAS DataBase Reference)
NIST Chemistry Reference2-Fluoro-6-methylpyridine(407-22-7)
Safety Information
Hazard Codes Xi,F
Risk Statements 36/37/38
Safety Statements 26-36
RIDADR 1993
WGK Germany 3
Hazard Note Flammable/Irritant
HazardClass IRRITANT
HS Code 29333990
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
2-Fluoro-6-methylpyridine Usage And Synthesis
Chemical Propertiesliquid
Uses2-Fluoro-6-methylpyridine may be used in the preparation of:
  • 2-fluoro-6-pyridinecarboxylic acid
  • 2,2′-[1-(6-methylpyridin-2-yl)ethane-1,1-diyl]dipyridine
  • 2-fluoropyridine-6-aldoxime
  • 2-fluoro-6-(dibromomethyl)pyridine
Synthesis Reference(s)Tetrahedron, 52, p. 23, 1996 DOI: 10.1016/0040-4020(95)00867-8
General Description2-Fluoro-6-methylpyridine, also known as 2-fluoro-6-picoline, can be prepared via diazotization of 2-amino-6-methylpyridine in hydrogen fluoride containing 40% pyridine solution. The effect of substituents on spectral properties of 2-fluoro-6-methylpyridine has been investigated based on 13C NMR, UV and IR spectral data.
2-Fluoro-6-methylpyridine Preparation Products And Raw materials
Raw materialsSodium nitrite-->Fluoroboric acid-->2-Amino-6-methylpyridine
Preparation Products2-Fluoro-6-formylpyridine

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