Anethole trithione

Anethole trithione
  • CAS No.:532-11-6
Other grades of this product :
Anethole trithione Basic information
Description
Product Name:Anethole trithione
Synonyms:Anetholi Trithionum;5-(4-methoxyphenyl)dithiole-3-thione;(E)-O-4-(prop-1-enyl)-5,6-dithioxocyclohexa-1,3-dienyl methanethioate;4-(prop-1-en-1-yl)-5,6-disulfanylidenecyclohexa-1,3-dien-1-yl carbothioate;Anethol trithione ,5-(4-Methoxyphenyl)-1,2-dithiole-3-thione;Anethali Trithinum;ANETHOLE TRITHIONE;5-(4-methoxyphenyl)-3h-1,2-dithiole-3-thione
CAS:532-11-6
MF:C10H8OS3
MW:240.36
EINECS:208-528-5
Product Categories:
Mol File:532-11-6.mol
Anethole trithione Chemical Properties
Melting point 111°
Boiling point 353.09°C (rough estimate)
density 1.4406 (rough estimate)
refractive index 1.5080 (estimate)
storage temp. 2-8°C
solubility soluble in Chloroform
form powder to crystal
color Orange-colored prisms from butyl acetate
Odorvery bitter taste
CAS DataBase Reference532-11-6(CAS DataBase Reference)
NIST Chemistry Reference3H-1,2-Dithiole-3-thione, 5-(4-methoxyphenyl)-(532-11-6)
Safety Information
ToxicityLD50 orl-mus: 3850 mg/kg NIIRDN 6,25,82
MSDS Information
Anethole trithione Usage And Synthesis
DescriptionAnise trisulfide, also known as bile vita, is a secretory choleretic drug, which can significantly enhance liver glutathione levels, significantly enhance glutamyl cysteine synthase, glutathione reductase and glutathione sulfur Transferase activity, reduce glutathione peroxidase activity, enhance liver cell viability, and increase bile secretion. Without increasing the burden on the liver, it can reduce liver portal pressure, eliminate liver congestion and other symptoms of hepatitis lesions, promote liver cell activation, and contribute to the improvement and recovery of liver function.
OriginatorSialor,Paladin Labs
Usescholeretic
Manufacturing Process1 mol anethol (1-methoxy-4-propenyl-benzene) and 3 mol sulfur were heated in an open vessel to temperature 190°-200°C. H2S was removed at this temperature. On cooling the reaction mixture was getting solid. The solid product was recrystallizated from acetone or ethanol to give the orange-red needles of 5-(4-methoxyphenyl)-3H-1,2-dithiole-3-thione; MP 108.5°C.
Therapeutic FunctionSalivation stimulant, Choleretic, Neuroprotective
Safety ProfilePoison by intramuscular route.Moderately toxic by ingestion and intraperitoneal routes.Experimental reproductive effects. When heated todecomposition it emits toxic fumes of SOx.
Anethole trithione Preparation Products And Raw materials
Raw materialsSulfur-->Butyl acetate-->cis-Anethol

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