tert-butyl 2-bromo-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine-5-carboxylate

CAS No.：365996-06-1

Other grades of this product :

tert-butyl 2-bromo-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate Basic information

Uses

Product Name:	tert-butyl 2-bromo-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
Synonyms:	tert-butyl 2-bromo-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate;tert-butyl 2-bromo-6,7-dihydro[1,3]thiazolo[5,4-c]pyridine-5(4H)-carboxylate;tert-butyl 2-broMo-6;2-BroMo-6,7-dihydro-4H-thiazolo[5,4-c]pyridine-5-carboxylicacidtert-butylester;2-Bromo-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine, N-BOC protected;Thiazolo[5,4-c]pyridine-5(4H)-carboxylic acid, 2-broMo-6,7-dihydro-, 1,1-diMethylethyl ester;tert-butyl 2-broMo-4H,5H,6H,7H-[1,3]thiazolo[5,4- c]pyridine-5-carboxylate;5-Boc-2-bromo-6,7-dihydro-4H-thiazolo[5,4-c]pyridine
CAS:	365996-06-1
MF:	C11H15BrN2O2S
MW:	319.22
EINECS:
Product Categories:	CHIRAL CHEMICALS;Heterocycle-Pyridine series
Mol File:	365996-06-1.mol

tert-butyl 2-bromo-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate Chemical Properties

Melting point	42-44 °C(Solv: ethyl ether (60-29-7))
Boiling point	390.9±42.0 °C(Predicted)
density	1.495±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
pka	1.23±0.20(Predicted)

Safety Information

Hazard Codes	T
Risk Statements	25
Safety Statements	45
RIDADR	UN2811
HS Code	2934100090

MSDS Information

tert-butyl 2-bromo-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate Usage And Synthesis

Uses	2-Bromo-5-(tert-butoxycarbonyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine is a reagent used for the synthesis of tetrahydrothiazolopyridines, which are potent antagonists for the smoothened (smo) receptor.

tert-butyl 2-bromo-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate Preparation Products And Raw materials

Raw materials

1-BOC-4-(1-PYRROLIDINYL)-3,6-DIHYDRO-2H-PYRIDINE-->3-BROMO-4-OXO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER-->TERT-BUTYL 2-AMINO-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDINE-5(4H)-CARBOXYLATE-->Cupric bromide-->Di-tert-butyl dicarbonate-->N-(tert-Butoxycarbonyl)-4-piperidone-->tert-Butyl nitrite

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