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| 2,6-Dihydroxypurine Basic information |
| Product Name: | 2,6-Dihydroxypurine | | Synonyms: | ISOXANTHINE;2,6-DIOXOPURINE;2,6-DIOXYPURINE;2,6-DIHYDROXYPURINE;9H-PURINE-2,6-DIOL;PURINE-2,6(1H,3H)-DIONE;TIMTEC-BB SBB004054;UREOUS ACID | | CAS: | 69-89-6 | | MF: | C5H4N4O2 | | MW: | 152.11 | | EINECS: | 200-718-6 | | Product Categories: | Heterocycles, Metabolites & Impurities;co-factor/nucleoside;Biochemistry;Nucleobases and their analogs;Nucleosides, Nucleotides & Related Reagents;Nucleic acids;Pyridines, Pyrimidines, Purines and Pteredines;Purine;Purines;Food Additives;Heterocycles;Metabolites & Impurities;bc0001 | | Mol File: | 69-89-6.mol |
| 2,6-Dihydroxypurine Chemical Properties |
| Melting point | 300 °C | | Boiling point | 274.55°C (rough estimate) | | density | 1.5452 (rough estimate) | | vapor density | 5.3 (vs air) | | refractive index | 1.8500 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | NH4OH: freely soluble | | pka | pKa 9.95 (Uncertain) | | form | Powder | | color | White to slightly yellow | | Odor | Odorless | | Water Solubility | Soluble in water(0.067g/L). | | Merck | 14,10059 | | BRN | 8733 | | InChIKey | LRFVTYWOQMYALW-UHFFFAOYSA-N | | CAS DataBase Reference | 69-89-6(CAS DataBase Reference) | | NIST Chemistry Reference | Xanthine(69-89-6) | | EPA Substance Registry System | Xanthine (69-89-6) |
| 2,6-Dihydroxypurine Usage And Synthesis |
| Chemical Properties | White to off-white crystalline powder | | Uses | 2,6-Dihydroxypurine was fund in animal organs, yeast, patatoes, coffee beans, tea. 2,6-Dihydroxypurine can be used to relax and widen certain breathing passages of the lungs. It is also found that a large number of derivatives have adenoside receptor antagonist properties.
| | Uses | Xanthine and xanthine oxidase system can be used to produce superoxide radicals. | | Definition | A poisonous colorless
crystalline organic compound that occurs
in blood, coffee beans, potatoes, and urine.
It is used as a chemical intermediate. | | Definition | Xanthine: a purine base, C5H4N4O2,found in many organisms. | | Synthesis Reference(s) | Chemical and Pharmaceutical Bulletin, 22, p. 1200, 1974 DOI: 10.1248/cpb.22.1200 | | General Description | Xanthine is a purine that can be produced in the purine metabolic pathway via different precursors:- Guanine deamination by guanine deaminase
- Hypoxanthine conversion by xanthine oxidoreductase
| | Biochem/physiol Actions | A high level of xanthine is implicated in metabolic disorders like Lesch-Nyhan syndrome. A xanthine-based biosensor may be useful for detecting xanthine in food and clinical samples. Blood and urine samples of patients with renal failure, gout and xanthinuria show high levels of xanthine. | | Purification Methods | The monohydrate separates in a microcrystalline form on slow acidification with acetic acid of a solution of xanthine in dilute NaOH. It is also precipitated by addition of conc NH3 to its solution in hot 2N HCl (charcoal). After washing with H2O and EtOH, it is dehydrated by heating above 125o. Its solubility in H2O is 1 in 14,000parts at 16o and 1 in 1,500parts of boiling H2O, and separates as plates . It has no m, but the perchlorate has m 262-264o [Lister Purines Part II, Fused Pyrimidines Brown Ed, Wiley-Interscience pp252-253 1971, ISBN 0-471-38205-1]. [Beilstein 26 H 447, 26 I 131, 26 II 260, 26 III/IV 2327.] |
| 2,6-Dihydroxypurine Preparation Products And Raw materials |
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