4-Amino-2-chloropyridine

4-Amino-2-chloropyridine
  • CAS No.:14432-12-3
Other grades of this product :
4-Amino-2-chloropyridine Basic information
Description
Product Name:4-Amino-2-chloropyridine
Synonyms:2-CHLORO-4-PYRIDINAMINE;2-CHLORO-4-AMINOPYRIDINE;2-CHLOROPYRIDIN-4-AMINE;2-CHLORO-PYRIDIN-4-YLAMINE;4-AMINO-2-CHLOROPYRIDINE;TIMTEC-BB SBB004235;4-Pyridinamine, 2-chloro-;2-CHLORO-4-AMINOPYRIDINE 97%
CAS:14432-12-3
MF:C5H5ClN2
MW:128.56
EINECS:238-403-0
Product Categories:API Intermediate;Aromatics;Pyridines derivates;Chloropyridines;Heterocycles;amine| alkyl chloride;PYRIDINE;FINE Chemical & INTERMEDIATES;Amines;Pyridines, Pyrimidines, Purines and Pteredines;Halopyridines;C5Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;blocks;Pyridines
Mol File:14432-12-3.mol
4-Amino-2-chloropyridine Chemical Properties
Melting point 90-94 °C(lit.)
Boiling point 153°C 5mm
density 1.2417 (rough estimate)
refractive index 1.5110 (estimate)
Fp 153°C/5mm
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka4.73±0.30(Predicted)
form Crystalline Powder
color Light yellow
Water Solubility Slightly soluble in water.
BRN 108671
InChIKeyBLBDTBCGPHPIJK-UHFFFAOYSA-N
CAS DataBase Reference14432-12-3(CAS DataBase Reference)
NIST Chemistry Reference4-Amino-2-chloropyridine(14432-12-3)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39-36/37/39
RIDADR 2811
WGK Germany 3
HazardClass IRRITANT
HS Code 29333999
MSDS Information
ProviderLanguage
2-Chloro-4-pyridinamine English
SigmaAldrich English
ACROS English
ALFA English
4-Amino-2-chloropyridine Usage And Synthesis
Description

4-Amino-2-chloropyridine is an important pharmaceutical and pesticide intermediate. It can synthesize N-(2-chloro-4-pyridyl)urea regulators that promote plant growth. It is also a key substance in the synthesis of KT-30 (Forchlorfenuron, IUPAC name N-(2-chloro-4-pyridyl)-N'-phenylurea). KT-30 is a highly active cytokinin, which has the biological activity of promoting tissue growth, promoting bud development and green preservation; it has an effect of increasing yield on apple, pear, grape, peach and other fruit crops. 4-Amino-2-chloropyridine itself can also be used as a pesticide alone, and has high activity against various pathogens such as rust, powdery mildew, rice blast, and apple downy mildew. 4-Amino-2-chloropyridine and its pharmaceutical and pesticide intermediates have the advantages of high biological activity, low toxicity, long-lasting period and easy degradation in the environment, so they have broad application prospects in agricultural production.

Chemical PropertiesWhite powder.
UsesAn aminopyridine derivative with potential herbicidal activity.
Uses4-Amino-2-chloropyridine may be used in the preparation of:
  • 3-deazacytosine
  • 7-substituted 1-alky-1,4-dihydro-4-oxo-1,6-naphthyridine-3-carboxylic acids
  • 1,6-naphthyridines
General Description4-Amino-2-chloropyridine is a chloroaminoheterocyclic compound. It readily undergoes Suzuki-Miyaura coupling with phenylboronic acid.

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