FMoc-NH-PEG9-CH2CH2COOH

CAS No.：1191064-81-9

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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FMoc-NH-PEG9-CH2CH2COOH Basic information

Product Name:	FMoc-NH-PEG9-CH2CH2COOH
Synonyms:	Fmoc-N-amido-PEG9-acid;Fmoc-N-amido-PEG10-acid;1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31-decaoxa-4-azatetratriacontan-34-oic acid;Fmoc-PEG9-propionic acid;FMoc-NH-PEG9-CH2CH2COOH;5,8,11,14,17,20,23,26,29-Nonaoxa-2-azadotriacontanedioic acid 1-(9H-fluoren-9-ylmethyl) ester;FMoc-NH-(PEG)₉-CH₂CH₂COOH;Fmoc-PEG9-CH2CH2COOH
CAS:	1191064-81-9
MF:	C36H53NO13
MW:	707.8
EINECS:
Product Categories:	peg
Mol File:	1191064-81-9.mol

FMoc-NH-PEG9-CH2CH2COOH Chemical Properties

Boiling point	803.9±65.0 °C(Predicted)
density	1.186±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.	2-8°C
solubility	Soluble in DMSO, DCM, DMF
pka	4.28±0.10(Predicted)

Safety Information

HS Code

2924297099

MSDS Information

FMoc-NH-PEG9-CH2CH2COOH Usage And Synthesis

Description

Fmoc-N-amido-PEG9-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Fmoc-N-amido-PEG9 Acid is used as a reactant in the synthesis of novel PEG-linked dimeric modulators for CXCR4.

FMoc-NH-PEG9-CH2CH2COOH Preparation Products And Raw materials

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