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| Methyl gallate Basic information |
| Product Name: | Methyl gallate | | Synonyms: | 3,4,5-trihydroxybenzoic acid methyl ester (intermediate of bifendate);METHYL GALLATE(METHYL 3,4,5-TRIHYDROXYBENZOATE );METHYLGALLATE(RG);2-diazo-1-naphthol-5-sulfonic acid, ester with novolac;METHYGALLATE;3,4,5-trihydroxy-benzoic acidd methyl ester;METHYL 3,4,5-TRIHYDROXYBENZOATE / METHYL GALLATE;Gallic acid methyl ester, Methyl 3,4,5-trihydroxybenzoate | | CAS: | 99-24-1 | | MF: | C8H8O5 | | MW: | 184.15 | | EINECS: | 202-741-7 | | Product Categories: | Food additive ,Antioxidant anticorrosive;(intermediate of bifendate);Photo Active Compounds;Aromatic Esters;Organic acids | | Mol File: | 99-24-1.mol |
| Methyl gallate Chemical Properties |
| Melting point | 201-204 °C | | Boiling point | 278.08°C (rough estimate) | | density | 1.3840 (rough estimate) | | refractive index | 1.5690 (estimate) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | ethanol: 50 mg/mL, clear | | form | Crystalline Powder | | pka | 8.04±0.23(Predicted) | | color | White to slightly beige | | Water Solubility | SOLUBLE IN HOT WATER | | Merck | 14,4345 | | BRN | 2113180 | | InChIKey | FBSFWRHWHYMIOG-UHFFFAOYSA-N | | CAS DataBase Reference | 99-24-1(CAS DataBase Reference) | | EPA Substance Registry System | Benzoic acid, 3,4,5-trihydroxy-, methyl ester (99-24-1) |
| Methyl gallate Usage And Synthesis |
| Description | Methyl gallate is a phenolic compound found in Terminalia myriocarpa and Geranium niveum. It is also found in wine. It is the methyl ester of gallic acid. | | Description | Methyl gallate is a phenol that has been found in Meliaceae and has diverse biological activities. It reduces adipogenic hormonal stimulation-induced lipid accumulation in 3T3-L1 cells when used at a concentration of 50 μM. Methyl gallate is active against V. cholerae in vitro (MIC = 32 μg/ml) and reduces V. cholerae-induced intestinal fluid accumulation in suckling mice when administered at doses of 50, 100, and 200 mg/kg. It reduces tumor growth and decreases the number of intratumor CD25+Foxp3high regulatory T cells (Tregs) in an EL-4 model of murine lymphoma. Methyl gallate (0.7, 7, and 70 mg/kg) reduces knee joint edema and leukocyte, neutrophil, and mononuclear cell infiltration in a mouse model of zymosan-induced arthritis. | | Chemical Properties | white to slightly beige crystalline powder | | Uses | Methyl gallate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD25+ regulatory T cells. | | Uses | The gallate ester methyl gallate is used as an antioxidant.
A ease was reported using a reprography paper.
| | Uses | Methyl 3,4,5-trihydroxybenzoate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD25+ regulatory T cells. | | Contact allergens | This ester of gallic acid is used as an antioxidant agent. A case was reported by using a reprography paper. | | Purification Methods | Methyl gallate [99-24-1] M 184.2, m 202o. Crystallise the gallate ester from MeOH. [Beilstein 10 IV 1998.] |
| Methyl gallate Preparation Products And Raw materials |
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