Securinol A

Securinol A
  • CAS No.:5008-48-0
Other grades of this product :
Securinol A Basic information
Product Name:Securinol A
Synonyms:Securinol A;Securinol;7H-5,10b-Ethano-2H-furo[2,3-a]quinolizin-2-one, 4,5,8,9,10,10a-hexahydro-12-hydroxy-, (5S,10aR,10bR,12R)-
CAS:5008-48-0
MF:C13H17NO3
MW:235.28
EINECS:
Product Categories:
Mol File:5008-48-0.mol
Securinol A Chemical Properties
Melting point 135-136℃
Boiling point 491.8±45.0 °C(Predicted)
density 1.37±0.1 g/cm3(Predicted)
pka14.31±0.20(Predicted)
Safety Information
MSDS Information
Securinol A Usage And Synthesis
DescriptionOne of three closely related alkaloid isolated from Securinega suffructicosa, the base has [α]17D + 58.2° (c 0.14, CHC13) or + 50° (dioxan). It yields a crystalline picrate, m.p. l86-7°C (dec.), and a 3: 5-dinitrobenzoate, m.p. 198-9°C;[α]17D + 55.3° (c 0.10, CHC13). On hydrogenation with Pt02 in AcOH it gives the dihydro derivative, forming a hydrochloride, m.p. 241- 2°C. When treated with methylsulphonyl chloride in pyridine, the base furnishes viroallosecurinine, m.p. 133- 4°C; [α]D + 1200° (c 0.01, EtOH).
ReferencesHorii et al., Chern. Pharrn. Bull., 13, 1307 (1965)
Securinol A Preparation Products And Raw materials

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