Dideoxyadenosine

Dideoxyadenosine
  • CAS No.:4097-22-7
Other grades of this product :
Dideoxyadenosine Basic information
Product Name:Dideoxyadenosine
Synonyms:[(2S,5R)-5-(6-Aminopurin-9-yl)oxolan-2-yl]methanol;NSC 98700;Didanosine Related CoMpound B;2',3'-DIDEOXYADENOSINE extapure;2’,3’-dideoxy-adenosin;2',3'-Dideoxy-D-adenosine;9-(2,3-Dideoxy-beta-D-ribofuranosyl)adenine;Didanosine Impurity 7(Didanosine EP Impurity G)
CAS:4097-22-7
MF:C10H13N5O2
MW:235.24
EINECS:223-853-2
Product Categories:Carbohydrates & Derivatives;Heterocycles;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Isotope Labelled Compounds;Antivirals for Research and Experimental Use;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Bases & Related Reagents
Mol File:4097-22-7.mol
Dideoxyadenosine Chemical Properties
Melting point 181-184 °C(lit.)
alpha D25 -25.2° (c = 1.01 in water)
Boiling point 377.64°C (rough estimate)
density 1.2455 (rough estimate)
refractive index -34 ° (C=1, H2O)
storage temp. -20°C
form Powder
pkapKa 3.84(H2O t=25.0±0. I=0.01) (Uncertain)
color White to Off-white
Water Solubility 43.2g/L(25 ºC)
Merck 14,3101
BRN 619924
InChIKeyWVXRAFOPTSTNLL-NKWVEPMBSA-N
CAS DataBase Reference4097-22-7(CAS DataBase Reference)
EPA Substance Registry SystemAdenosine, 2',3'-dideoxy- (4097-22-7)
Safety Information
Hazard Codes C
Risk Statements 34-36/37-22
Safety Statements 26-27-36/37/39-45-24/25
WGK Germany 2
RTECS AU7358900
HS Code 29349990
ToxicityLD50 oral in mouse: 5gm/kg
MSDS Information
ProviderLanguage
2',3'-Dideoxy-adenosine English
SigmaAldrich English
Dideoxyadenosine Usage And Synthesis
Chemical PropertiesBeige power
UsesA potent labelled anti-HIV agent.
UsesA potent anti-HIV agent.
UsesDideoxy Adenosine (Didanosine EP Impurity G) is a potent anti-HIV agent.
Uses2′,3′-Dideoxyadenosine (ddA), a specific adenylyl cyclase inhibitor, is useful in biological process and pathway studies involving adenylyl cyclase activity and cAMP pool modulation.
DefinitionChEBI: A purine 2',3'-dideoxyribonucleoside in which the nucleobase component is specified as adenine.
General DescriptionOff-white powder.
Air & Water ReactionsWater soluble.
Reactivity ProfileDideoxyadenosine may be sensitive to prolonged exposure to light.
Health HazardSYMPTOMS: Symptoms of exposure to a related compound include cutaneous eruptions, fever, mouth sores, thrombocytopenia, neutropenia, reversible peripheral neuropathy, gastrointestinal distress, headache, nausea and vomiting.
Fire HazardFlash point data for Dideoxyadenosine are not available; however, Dideoxyadenosine is probably combustible.
Dideoxyadenosine Preparation Products And Raw materials

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