ERIOCITRIN

ERIOCITRIN
  • CAS No.:13463-28-0

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
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ERIOCITRIN Basic information
Product Name:ERIOCITRIN
Synonyms:(S)-3',4',5,7-TETRAHYDROXYFLAVANONE-7-[6-O-(ALPHA-L-RHAMNOPYRANOSYL)-BETA-D-GLUCOPYRANOSIDE];ERIOCITRIN;ERIODICTYL-7-RUTINOSIDE;ERIODICTYOL-7-O-RUTINOSIDE;ERIODICTYOL-7-RUTINOSIDE;(s)-3',4',5,7-tetrahydroxyflavanone-7-[6-o-(α-l-rhamnopyranosyl)-β-d-glucopyranoside];(2S)-2-(3,4-dihydroxyphenyl)-5-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxymethyl]oxan-2-yl]oxy-chroman-4-one;ERIOCITRIN(SH)
CAS:13463-28-0
MF:C27H32O15
MW:596.53
EINECS:236-668-7
Product Categories:chemical reagent;pharmaceutical intermediate;Flavanones;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol File:13463-28-0.mol
ERIOCITRIN Chemical Properties
Melting point 161-190°C
Boiling point 956.9±65.0 °C(Predicted)
density 1.77
storage temp. Inert atmosphere,2-8°C
solubility DMSO (Slightly), Methanol
pka7.15±0.40(Predicted)
form neat
color Dark Beige to Very Dark Beige
BRN 1304401
CAS DataBase Reference13463-28-0(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
F 10-21
HS Code 29389090
MSDS Information
ProviderLanguage
SigmaAldrich English
ERIOCITRIN Usage And Synthesis
DescriptionEriocitrin is a flavonoid originally isolated from lemon peel that has antioxidant and enzyme inhibitory activity. Eriocitrin inhibits lipid peroxidation in a cell-free assay when used at a concentration of 10 μM and enhances the effect of α-tocopherol on lipid peroxidation. It also decreases thiobarbituric acid reactive substances (TBARS) in rat plasma when administered at a dose of 75 μmol/kg, indicating a reduction in lipid peroxidation. Eriocitrin prevents acute exercise-induced increases in TBARS, Nε-(hexanoyl)lysine (HEL), o,o-dityrosine (DT), and nitrotyrosine (NT; ) in rat liver when administered at a dose of 600 mg/kg prior to exercise. It is also an inhibitor of monoamine oxidase A (MAO-A) and MAO-B (IC50s = 86.5 and 164 μM, respectively, for human recombinant receptors).
Chemical Propertiessolid
UsesEriocitrin is one of the main flavonoids in citrus limon byproduct dried powder (CBP) that exhibits antioxidant activity.
DefinitionChEBI: A disaccharide derivative that consists of eriodictyol substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage
ERIOCITRIN Preparation Products And Raw materials

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