2-Nitroimidazole

CAS No.：527-73-1

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

View the full Disclaimer

Other grades of this product :

2-Nitroimidazole Basic information

Product Name:	2-Nitroimidazole
Synonyms:	ro05-9129;2-Nitroimidazole,98%;2-Nitroimidaxole;2-nitro-imidazo;2-NITROMIDAZOLE;1H-Imidazole, 2-nitro-;AzoMycin (2-NitroiMidazole);2-Nitroimidazole sulfate
CAS:	527-73-1
MF:	C3H3N3O2
MW:	113.07
EINECS:	208-425-5
Product Categories:	Heterocycles;Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines;Imidazol&Benzimidazole;Heterocyclic Compounds;Imidaxoles;Building Blocks;C3 to C8;Chemical Synthesis;Heterocyclic Building Blocks;Imidazoles;OLED materials,pharm chemical,electronic;Pharmaceutical intermediates;Inhibitors
Mol File:	527-73-1.mol

2-Nitroimidazole Chemical Properties

Melting point	287 °C (dec.) (lit.)
Boiling point	211.75°C (rough estimate)
density	1.5988 (rough estimate)
refractive index	1.4264 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	NH4OH: soluble50mg/mL, clear, yellow to orange
form	Powder
pka	8.72±0.10(Predicted)
color	Light yellow to khaki-green
Water Solubility	insoluble
Merck	14,921
BRN	116444
InChIKey	YZEUHQHUFTYLPH-UHFFFAOYSA-N
CAS DataBase Reference	527-73-1(CAS DataBase Reference)
EPA Substance Registry System	1H-Imidazole, 2-nitro- (527-73-1)

Safety Information

Hazard Codes	Xn,T
Risk Statements	22-36/37/38-23/24/25-20/21/22
Safety Statements	26-36-45-36/37/39
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	NI7875000
TSCA	Yes
HazardClass	6.1
PackingGroup	III
HS Code	29332990
Toxicity	LD50 i.v. in mice: 80 mg/kg (Maeda)

MSDS Information

Provider	Language
Azomycin	English
SigmaAldrich	English
ACROS	English
ALFA	English

2-Nitroimidazole Usage And Synthesis

Chemical Properties	Pale Yellow Solid
Uses	2-Nitroimidazole is a antibiotic substance produced by an unidentified Streptomyces,it is used to prepare nitroimidazole substituted boronic acids as precursors for imaging hypoxic tissue 1.It is also used to prepare potential site-selective radiosensitizers for estrogen receptor-rich tumors.
Uses	2-Nitroimidazole, is used as an antibiotic in pharma industry.
Uses	Antibiotic substance produced by an unidentified Streptomyces
Definition	ChEBI: An imidazole that is 1H-imidazole substituted at position 2 by a nitro group.
General Description	2-Nitroimidazole is a natural antibiotic.

2-Nitroimidazole Preparation Products And Raw materials

Raw materials	Ethanol-->Ethyl acetate-->Diethyl ether-->PETROLEUM ETHER-->Nitric acid-->Sodium nitrite-->Sodium sulfate-->Fluoroboric acid-->Copper(II) sulfate pentahydrate-->2,2-Diethoxyethylamine-->2-Aminoimidazole hemisulfate-->2-Aminoimidazole
Preparation Products	2-Aminoimidazole-->2-nitro-1-(prop-2-ynyl)-1H-imidazole

Welcome！

Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.

NO. 18 ,Wujiang Road, Wulidian Street, Jiangbei District, Chongqing
+86-23-6139-8061 +86-13650506873
danny@chemdad.com sales@chemdad.com
www.chemdad.com
WhatsApp +86-13650506873