Dimethachlon

CAS No.：24096-53-5

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Dimethachlon Basic information

Product Name:	Dimethachlon
Synonyms:	DIMETHACHLON;1-(3,5-dichlorophenyl)-5-pyrrolidinedione;N-(3,5-DICHLOROPHENYL)-SUCCINIMIDE;5-Pyrrolidinedione,1-(3,5-dichlorophenyl)-2;ohric;s-47127;4-ethyl-2-methoxy-1-[4-[2-(sulfothio)ethylamino]butoxy]benzene;2,5-Pyrrolidinedione,1-(3,5-dichlorophenyl)-
CAS:	24096-53-5
MF:	C10H7Cl2NO2
MW:	244.07
EINECS:	601-478-9
Product Categories:	FUNGICIDE
Mol File:	24096-53-5.mol

Dimethachlon Chemical Properties

Melting point	136～140℃
Boiling point	493.9±35.0 °C(Predicted)
density	1.4043 (rough estimate)
refractive index	1.6100 (estimate)
pka	-2.68±0.20(Predicted)
CAS DataBase Reference	24096-53-5

Safety Information

HS Code

29251900

MSDS Information

Dimethachlon Usage And Synthesis

Chemical Properties	white crystalline powder
Uses	Dimethachlon is a fungicide found in pesticide compositions and is used in the treatment of necrotrophic fungal pathogen Sclerotinia sclerotiorum.
Metabolic pathway	The nephrotoxicant, N-(3,5-dichlorophenyl)succinimide (NDPS), undergoes non-enzymatic hydrolysis to N- (3,5-dichlorophenyl)succinamic acid (NDPSA) in buffer, rat liver and kidney homogenates, and rabbit liver homogenates. In the presence of NADPH, rat liver homogenates convert NDPS to NDPSA and N- (3,5-dichlorophenyl)-2-hydroxysuccinamic acid (2- NDHSA). Using liver homogenates from phenobarbital- treated rats, N-(3,5-dichlorophenyl)-3- hydroxysuccinimide (NDHS) and N-(3,5- dichlorophenyl)-3-hydroxysuccinamic acid (3-NDHSA) are also detected.

Dimethachlon Preparation Products And Raw materials

Raw materials

Succinic acid-->3,5-Dichloroaniline-->1,4-DIAMINOBUTANE

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