Nitrosobenzene

CAS No.：586-96-9

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Nitrosobenzene Basic information

Product Name:	Nitrosobenzene
Synonyms:	Nitrosobenzene >=97%;NITROSOBENZENE;benzene,nitroso-;nitroso-benzen;nob;Nitrosobenzol;1-Nitrosobenzene;p-nitrosobenzene
CAS:	586-96-9
MF:	C6H5NO
MW:	107.11
EINECS:	209-591-1
Product Categories:	Organic Building Blocks;Analytical Chemistry;ESR Spectrometry;Spin Trapping Reagents;Building Blocks;Chemical Synthesis;Nitrogen Compounds;Nitroso Compounds
Mol File:	586-96-9.mol

Nitrosobenzene Chemical Properties

Melting point	65-69 °C (lit.)
Boiling point	59 °C/18 mmHg (lit.)
density	1.1697 (rough estimate)
refractive index	1.5389 (estimate)
storage temp.	2-8°C
solubility	Chloroform (Sparingly), Methanol (Slightly)
form	Solid
color	White to Brown
BRN	605688
Stability:	Stable. Incompatible with strong oxidizing agents.
InChIKey	NLRKCXQQSUWLCH-UHFFFAOYSA-N
CAS DataBase Reference	586-96-9
NIST Chemistry Reference	Benzene, nitroso-(586-96-9)
EPA Substance Registry System	Nitrosobenzene (586-96-9)

Safety Information

Hazard Codes	T
Risk Statements	20/21-25
Safety Statements	26-36/37-45
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	DA6497525
F	9-23
HazardClass	6.1(b)
PackingGroup	III
HS Code	29042000

MSDS Information

Provider	Language
Nitrosobenzene	English
SigmaAldrich	English

Nitrosobenzene Usage And Synthesis

Chemical Properties	light yellow solid
Uses	Spin trap reagent. Has been used in the study of oxidative DNA damage and nitroso-compound-induced respiratory burst in neutrophils3,4.
Uses	Spin trap. Undergoes various addition, reduction, and oxidation reactions.
Definition	ChEBI: A nitroso compound that is the nitroso derivative of benzene; a diamagnetic hybrid of singlet O2 and azobenzene.
Purification Methods	Steam distil nitrosobenzene, then crystallise it from a small volume of EtOH with cooling below 0o, dry it over CaCl2 in a dessicator at atmospheric pressure, and store it under N2 at 0o. Alternatively it can be distilled onto a cold finger cooled with brine at ~-10o in a vacuum at 17mm (water pump), while heating in a water bath at 65-70o [Robertson & Vaughan J Chem Educ 27 605 1950]. [Beilstein 5 IV 702.]

Nitrosobenzene Preparation Products And Raw materials

Raw materials	(E)-1,2-Diphenyldiazene-->AZOXYBENZENE-->Aniline-->N-Phenylhydroxylamine
Preparation Products	Nitrobenzene-->Aniline-->N-Phenylhydroxylamine-->Benzaldehyde-->[1,1':2',1''-Terphenyl]-4'-amine

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