N-Acetyl-L-proline

CAS No.：68-95-1

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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N-Acetyl-L-proline Basic information

Product Name:	N-Acetyl-L-proline
Synonyms:	N-AN-Acetyl-L-prolineN-Acetyl-L-prolinecetyl-L-proline;(2S)-1-acetyl-2-pyrrolidinecarboxylate;(S)-N-Acetylproline;L-N-Acetylproline;NSC 280718;N-Ac-Pro-OH;ASINEX-REAG BAS 16579166;ACETYL-L-PROLINE
CAS:	68-95-1
MF:	C7H11NO3
MW:	157.17
EINECS:	200-698-9
Product Categories:	A - H;Amino Acids;chiral;Amino Acid Derivatives;Amino Acids;Modified Amino Acids;ACETYLGROUP;PYRROLE;pharmacetical;N-Acetyl-Amino acid series;amino;bc0001
Mol File:	68-95-1.mol

N-Acetyl-L-proline Chemical Properties

Melting point	115-117 °C
alpha	-86 º (c=1 EtOH)
Boiling point	366.2±35.0 °C(Predicted)
density	1.274±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
pka	3.69±0.20(Predicted)
form	Powder
color	White to off-white
BRN	83200
InChIKey	GNMSLDIYJOSUSW-LURJTMIESA-N
CAS DataBase Reference	68-95-1(CAS DataBase Reference)
NIST Chemistry Reference	L-proline, 1-acetyl-(68-95-1)

Safety Information

Hazard Codes	Xi
Safety Statements	24/25
WGK Germany	3
HazardClass	IRRITANT
HS Code	29339900

MSDS Information

Provider	Language
N-Acetyl-L-proline	English
ACROS	English
SigmaAldrich	English
ALFA	English

N-Acetyl-L-proline Usage And Synthesis

Chemical Properties	white to off-white powder
Uses	N-Acetyl-L-proline is an aminoacid used in the synthesis of pharmaceutical compounds useful in preventing and treating disorders and syndromes associated with the nervous, vascular, musculoskeletal, o r cutaneous systems.
Biochem/physiol Actions	N-acetyl-L-proline is an analog of the COOH-terminal dipeptide portion of preferred substrates of angiotensin-converting enzyme (ACE). It may be used in studies of the binding of substrates and inhibitors by ACE and to differentiate the specificities of various aminoacylases.

N-Acetyl-L-proline Preparation Products And Raw materials

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