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| Product Name: | FORSYTHOSIDE A | | Synonyms: | 2-(3,4-Dihydroxyphenyl)ethyl 6-O-(6-deoxy-α-L-mannopyranosyl)-4-O-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]carbonyl-β-D-glucopyranoside;FORSYTHOSIDE A;Forsythiaside A;Forsythiaside;b-D-Glucopyranoside,2-(3,4-dihydroxyphenyl)ethyl 6-O-(6-deoxy-a-L-Mannopyranosyl)-,4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate];Forsythoside A, 98%, from Forsythia suspensa;Forsythoside A 79916-77-1;β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 6-O-(6-deoxy-α-L-mannopyranosyl)-, 4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate] | | CAS: | 79916-77-1 | | MF: | C29H36O15 | | MW: | 624.59 | | EINECS: | | Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract | | Mol File: | 79916-77-1.mol |
| FORSYTHOSIDE A Chemical Properties |
| Melting point | >127°C (subl.) | | Boiling point | 911.9±65.0 °C(Predicted) | | density | 1.60±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 9.31±0.10(Predicted) | | color | Off-White to Light Beige | | CAS DataBase Reference | 79916-77-1 |
| FORSYTHOSIDE A Usage And Synthesis |
| Overview | Forsythiaside A is the phenylethanol glycoside component isolated from Forsythia. It has pharmacological effects such as antibacterial, antiviral, antioxidant, anti-infective and antipyretic. It is mainly used for content determination, identification, and pharmacological experiment and so on.
| | Chemical Properties | This product appears as white crystalline powder. It is easily soluble in water, ethanol and methanol, but insoluble in ether and chloroform.
| | Pharmacological effects | Forsythoside A has not only antibacterial, anti-infective and antipyretic effects, but also good anti-virus and antioxidant effects.
| | Preparation | Extract 40 g of crushed forsythia leaves with 1200 mL 55% ethanol (volume fraction) at 74 ° C for 50 min, filter and extract twice. The filtrate was combined and concentrated under reduced pressure at 50 °C to recycle the ethanol, obtaining 665 mL of concentrated solution. 35 mL of absolute ethanol was added to give a forsythia leaf extract containing 5% ethanol (volume fraction). The forsythia leaf extract was adsorbed on a 2.6 cm x 25 cm AB-8 resin column and eluted with 50% ethanol to obtain a forsythia leaf extract. The extract of forsythia leaf was extracted for three times with water-saturated n-butanol. Recycle the n-butanol, and dry to obtain crude product. The crude product was separated in 8 cm x 50 cm C18 reverse phase silica gel column chromatography through elution with 30% methanol. Collect the eluent and obtain the pure compound of forsythoside A under reduced pressure.
| | Application | It can be used for content determination, identification and pharmacological experiments.
| | Uses | Forsythoside A is used as an antiinflammatory agent in traditional Chinese medicine. | | Biological Activity | extracted from forsythia suspense (thunb.) vahl dried fruit;store the product in sealed, cool and dry condition |
| FORSYTHOSIDE A Preparation Products And Raw materials |
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